.jpg "HCG-alpha IHC human Placenta (HCGa 53)")
PDF DatasheetHuman Anti-HCG-alpha Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-HCG-alpha Antibody Clone: HCGa/53
Clone HCGa/53 Host and Isotype: Mouse IgG1 kappa
Anti-Human HCG-alpha Positive Control Sample: JAR or TT Cells. Placenta
Cellular Localization of Antibody Cytoplasmic, secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant hCG alpha protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
HCG-alpha Previously Observed Antibody Staining Patterns
Observed Antibody Staining Data By Tissue Type:
Variations in HCG-alpha antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in cells in the anterior in pituitary gland and trophoblastic cells in the placenta. More moderate antibody staining intensity was present in cells in the anterior in pituitary gland and trophoblastic cells in the placenta. Low, but measureable presence of HCG-alpha could be seen in. We were unable to detect HCG-alpha in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.
| HCG-alpha General Information | |
|---|---|
| Alternate Names | |
| beta globin, haemoglobin beta, hemoglobin beta | |
| Molecular Weight | |
| ~13kDa | |
| Chromosomal Location | |
| 6q12-q21 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CGA |
| Entrez Gene ID | 1081 |
| Ensemble Gene ID | ENSG00000135346 |
| RefSeq Protein Accession(s) | NP_001239312, NP_000726 |
| RefSeq mRNA Accession(s) | NM_001252383, NM_000735 |
| RefSeq Genomic Accession(s) | NC_000006, NC_018917 |
| UniProt ID(s) | P01215, Q6I9S8, A0A087WYZ4 |
| UniGene ID(s) | P01215, Q6I9S8, A0A087WYZ4 |
| HGNC ID(s) | 1885 |
| Cosmic ID(s) | CGA |
| KEGG Gene ID(s) | hsa:1081 |
| PharmGKB ID(s) | PA26433 |
| General Description of HCG-alpha. | |
| This MAb reacts with a protein of ~13kDa, identified as alpha sub-unit of HCG. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the ?, ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). | |
Limitations and Warranty
enQuire Bio’s HCG-alpha Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
-150x150.jpg)
There are no reviews yet.