.jpg "Human Chorionic Gonadotropin IHC human Placenta (HCGab 52)")
PDF DatasheetHuman Anti-Human Chorionic Gonadotropin Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Human Chorionic Gonadotropin Antibody Clone: HCGab/52
Clone HCGab/52 Host and Isotype: Mouse IgG1 kappa
Anti-Human Human Chorionic Gonadotropin Positive Control Sample: JAR or TT Cells. Placenta
Cellular Localization of Antibody Cytoplasmic, Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Purified hCG protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Human Chorionic Gonadotropin Previously Observed Antibody Staining Patterns
| Human Chorionic Gonadotropin General Information | |
|---|---|
| Alternate Names | |
| Chorionic Gonadotropin, hCG | |
| Molecular Weight | |
| ~35kDa (intact hCG) | |
| Chromosomal Location | |
| 6q12-q21 (HCG-alpha) & 19q13.33 (HCG-beta) | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CGA (HCG-alpha) & CGB (HCG-beta) |
| Entrez Gene ID | 1081, 1082 |
| Ensemble Gene ID | ENSG00000135346, ENSG00000104827 |
| RefSeq Protein Accession(s) | NP_001239312, NP_000726, NP_000728 |
| RefSeq mRNA Accession(s) | NM_001252383, NM_000735NM_000737 |
| RefSeq Genomic Accession(s) | NC_000006, NC_018917NC_000019, NC_018930 |
| UniProt ID(s) | P01215, Q6I9S8, A0A087WYZ4, P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0 |
| UniGene ID(s) | P01215, Q6I9S8, A0A087WYZ4, P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0 |
| HGNC ID(s) | 1885, 1886 |
| Cosmic ID(s) | CGA, CGB3 |
| KEGG Gene ID(s) | hsa:1081, hsa:1082 |
| PharmGKB ID(s) | PA26433 |
| General Description of Human Chorionic Gonadotropin. | |
| This MAb is a very special because it reacts ONLY with the intact-HCG, not with either free alpha- or free beta-chain of HCG. HCG is a glycoprotein, is composed of two non-identical, non-covalently linked polypeptide chains designated as the ? , ? subunits. The ? subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). HCG is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. HCG expression by non-trophoblastic tumors may indicate aggressive behavior. | |
Limitations and Warranty
enQuire Bio’s Human Chorionic Gonadotropin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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