PDF DatasheetHuman, Cow, Pig, Rabbit, Mouse, and Rat (-) Anti-Insulin / IRDN Antibody Product Attributes
Species: Human, Cow, Pig, Rabbit, Mouse, and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Insulin / IRDN Antibody Clone: IRDN/805
Clone IRDN/805 Host and Isotype: Mouse IgG1 kappa
Anti-Human, Cow, Pig, Rabbit, Mouse, and Rat (-) Insulin / IRDN Positive Control Sample: MIA PaCa-2 cells or Pancreas
Cellular Localization of Antibody Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant INS protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Insulin / IRDN Previously Observed Antibody Staining Patterns
| Insulin / IRDN General Information | |
|---|---|
| Alternate Names | |
| INS, Insulin | |
| Molecular Weight | |
| 6kDa | |
| Chromosomal Location | |
| 11p15.5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | INS |
| Entrez Gene ID | 3630 |
| Ensemble Gene ID | ENSG00000254647 |
| RefSeq Protein Accession(s) | NP_001278826, NP_001172026, NP_000198, NP_001172027 |
| RefSeq mRNA Accession(s) | NM_001291897, NM_001185097, NM_000207, NM_001185098 |
| RefSeq Genomic Accession(s) | NC_018922, NG_007114, NC_000011, NG_050578 |
| UniProt ID(s) | I3WAC9, P01308 |
| UniGene ID(s) | I3WAC9, P01308 |
| HGNC ID(s) | 6081 |
| Cosmic ID(s) | INS |
| KEGG Gene ID(s) | hsa:3630 |
| PharmGKB ID(s) | PA201 |
| General Description of Insulin / IRDN. | |
| Recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A, B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule, the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids,, certain ions. It also promotes glycogen storage, formation of triglycerides,, synthesis of proteins, nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell, insulinoma marker. | |
Limitations and Warranty
enQuire Bio’s Insulin / IRDN Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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