PDF DatasheetHuman Anti-MUC2 Antibody Product Attributes
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (1-2ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-MUC2 Antibody Clone: SPM513
Clone SPM513 Host and Isotype: Mouse IgG1 kappa
Anti-Human MUC2 Positive Control Sample: LS174T cells or small intestine.
Cellular Localization of Antibody Cytoplasmic, cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: A synthetic peptide of 29 amino acids, KYPTTTPISTTTMVTPTPTPTGTQTPTTT from MUC2 protein, coupled to KLH.
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
MUC2 Previously Observed Antibody Staining Patterns
| MUC2 General Information | |
|---|---|
| Alternate Names | |
| Mucin 2, MUC2 | |
| Molecular Weight | |
| 520kDa | |
| Chromosomal Location | |
| 11p15.5 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MUC2 |
| Entrez Gene ID | 4583 |
| RefSeq Protein Accession(s) | NP_002448 |
| RefSeq mRNA Accession(s) | NM_002457 |
| RefSeq Genomic Accession(s) | NG_187681, NG_051929, NW_015148966, NC_000011, NC_018922 |
| UniGene ID(s) | |
| HGNC ID(s) | 7512 |
| Cosmic ID(s) | MUC2 |
| KEGG Gene ID(s) | hsa:4583 |
| General Description of MUC2. | |
| Recognizes a single glycoprotein of 520kDa, identified as mucin 2 (MUC2). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC3. Its epitope has been defined as GTQTP (GlyThrGlnThrPro). Mucins are high molecular weight glycoproteins, which constitute the major component of the mucus layer that protects the gastric epithelium. MUC2 is specifically expressed in goblet cells of the small intestine & colon; in about 65% of colonic carcinomas, about 40% of gastric carcinomas. MUC2 is rarely expressed outside of the GI tract with the exceptions of mucinous carcinoma of breast, clear cell-type carcinomas of the ovary. | |
Limitations and Warranty
enQuire Bio’s MUC2 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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