PDF DatasheetAntibody (Suitable for clinical applications)
| Specification | Recommendation |
|---|---|
| Recommended Dilution (Conc) | 1:50-1:100 |
| Pretreatment | EDTA Buffer pH8.0 |
| Incubation Parameters | 30 min at Room Temperature |
Prior to use, inspect vial for the presence of any precipitate or other unusual physical properties. These can indicate that the antibody has degraded and is no longer suitable for patient samples. Please run positive and negative controls simultaneously with all patient samples to account and control for errors in laboratory procedure. Use of methods or materials not recommended by enQuire Bio including change to dilution range and detection system should be routinely validated by the user.
Myogenin Information for Pathologists
Summary:
Myogenic transcriptional regulatory protein expressed early in skeletal muscle differentiation. Sensitive and specific for rhabdomyosarcoma. Focal nuclear staining in desmoid tumors, infantile myofibromatosis, synovial sarcoma, infantile fibrosarcoma, entrapped atrophic or regenerative skeletal muscle (Am J Surg Pathol 2001;25:1150). Microscopic (histologic) images Missing Image.
| Myogenin General Information | |
|---|---|
| Alternate Names | |
| Molecular Weight | |
| 25 kDa | |
| Chromosomal Location | |
| q32.1 [chr: 1] [chr_start: 203083129] [chr_end: 203086012] [strand: -1] | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MYOG |
| Entrez Gene ID | 4656 |
| RefSeq Protein Accession(s) | NP_002470 |
| RefSeq mRNA Accession(s) | NM_002479 |
| RefSeq Genomic Accession(s) | NC_000001 |
| UniProt ID(s) | P15173 |
| PharmGKB ID(s) | PA31417 |
| KEGG Gene ID(s) | hsa:4656 |
| General Description of Myogenin . | |
| This antibody is specific to 34 kDa protein known as myogenin. Myogenin is a member of family of myogenic regulatory genes which includes MyoD, myf5 and MRF4. These genes encode a set of transcription factors which are essential for muscle development. Expression of myogenin is restricted to cells of skeletal muscle origin. | |
There are no reviews yet.