PDF DatasheetHuman Anti-PAX7 Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-PAX7 Antibody Clone: PAX7/1187
Clone PAX7/1187 Host and Isotype: Mouse IgG1 kappa
Anti-Human PAX7 Positive Control Sample: Rhabdomyosarcoma (RMS) or Testicular Carcinoma
Cellular Localization of Antibody Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant fragment (aa300-600) of human PAX7 protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
PAX7 Previously Observed Antibody Staining Patterns
| PAX7 General Information | |
|---|---|
| Alternate Names | |
| Paired box protein Pax-7, PAX7 | |
| Molecular Weight | |
| 57kDa | |
| Chromosomal Location | |
| 1p36.13 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PAX7 |
| Entrez Gene ID | 5081 |
| Ensemble Gene ID | ENSG00000009709 |
| RefSeq Protein Accession(s) | NP_001128726, NP_002575, NP_039236 |
| RefSeq mRNA Accession(s) | NM_013945, NM_002584 NM_001135254 |
| RefSeq Genomic Accession(s) | NC_000001, NG_023262, NC_018912 |
| UniProt ID(s) | P23759 |
| UniGene ID(s) | P23759 |
| HGNC ID(s) | 8621 |
| Cosmic ID(s) | PAX7 |
| KEGG Gene ID(s) | hsa:5081 |
| PharmGKB ID(s) | PA32961 |
| General Description of PAX7. | |
| The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal, position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease, cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma). | |
Limitations and Warranty
enQuire Bio’s PAX7 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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