PDF DatasheetHuman Anti-Prolactin Receptor Antibody Product Attributes
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Prolactin Receptor Antibody Clone: B6.2 + PRLR742
Clone B6.2 + PRLR742 Host and Isotype: Mouse IgG
Anti-Human Prolactin Receptor Positive Control Sample: Testicular Carcinoma
Cellular Localization of Antibody Cell surface, cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Semi-purified human prolactin receptor (B6.2); Recombinant human prolactin receptor (PRLR742)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Prolactin Receptor Previously Observed Antibody Staining Patterns
| Prolactin Receptor General Information | |
|---|---|
| Alternate Names | |
| Prolactin Receptor, PRLR | |
| Molecular Weight | |
| 70kDa | |
| Chromosomal Location | |
| 5p13.2 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | PRLR |
| Entrez Gene ID | 5618 |
| Ensemble Gene ID | ENSG00000113494 |
| RefSeq Protein Accession(s) | XP_016865135, NP_001191243, NP_001191244, NP_001191246, NP_001191247, XP_011512370, XP_011512371, XP_016865134, NP_001191245, XP_006714547, NP_000940 |
| RefSeq mRNA Accession(s) | NM_001204314, XM_006714484, XM_017009645 NM_000949, NM_001204317, XM_011514068, XM_017009646, XM_011514069, NM_001204315, NM_001204316, NM_001204318, NR_037910 |
| RefSeq Genomic Accession(s) | NG_029042, NC_000005, NC_018916 |
| UniProt ID(s) | P16471 |
| UniGene ID(s) | P16471 |
| HGNC ID(s) | 9446 |
| Cosmic ID(s) | PRLR |
| KEGG Gene ID(s) | hsa:5618 |
| PharmGKB ID(s) | PA33791 |
| General Description of Prolactin Receptor. | |
| It recognizes a protein of 70kDa, identified as prolactin receptor. Prolactin is a pituitary hormone involved in the stimulation of milk production, salt, water regulation, growth, development, reproduction. The initial step in its action is the binding to a specific membrane receptor (prolactin receptor), which belongs to the superfamily of class 1 cytokine receptors. The function of the prolactin receptor is mediated, at least in part, by two families of signaling molecules: Janus kinases, signal transducers, activators of transcription. | |
Limitations and Warranty
enQuire Bio’s Prolactin Receptor Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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