Anti-Rb1 Antibody Clone 1F8

Observed Subcellular, Organelle Specific Staining Data:

Variations in Rb1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the adrenal gland and breast, Purkinje cells in the cerebellum, glandular cells in the cervix, uterine, non-germinal center cells in the lymph node, decidual cells in the placenta, cells in the inner nuclear layer in retina, cells in the photoreceptor layer in retina, ganglion cells in the retina, melanocytes in skin, glandular cells in the thyroid gland, non-germinal center cells in the tonsil and squamous epithelial cells in the vagina. More moderate antibody staining intensity was present in glandular cells in the adrenal gland and breast, Purkinje cells in the cerebellum, glandular cells in the cervix, uterine, non-germinal center cells in the lymph node, decidual cells in the placenta, cells in the inner nuclear layer in retina, cells in the photoreceptor layer in retina, ganglion cells in the retina, melanocytes in skin, glandular cells in the thyroid gland, non-germinal center cells in the tonsil and squamous epithelial cells in the vagina. Low, but measureable presence of Rb1 could be seen inlymphoid tissue in appendix, adipocytes in breast, myoepithelial cells in the breast, neuronal cells in the caudate nucleus, endothelial cells in the colon, cells in the endometrial stroma in endometrium, glandular cells in the endometrium, islets of Langerhans in pancreas, glandular cells in the prostate and cells in the red pulp in spleen. We were unable to detect Rb1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.