PDF DatasheetHuman Anti-Sex Hormone Binding Globulin Antibody Product Attributes
Species: Human
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).
Application Notes: Flow Cytometry (0.5-1ug of antibody/million cells in 0.1ml), Immunofluorescence (0.5-1ug of antibody/ml), Immunohistochemistry (IHC) (Formalin-fixed) (1-2ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-Sex Hormone Binding Globulin Antibody Clone: SPM605
Clone SPM605 Host and Isotype: Mouse IgG1
Anti-Human Sex Hormone Binding Globulin Positive Control Sample: Liver, Placenta or Testis
Cellular Localization of Antibody Cytoplasmic & Extracellular (Secreted)
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant full-length human SHBG protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
Sex Hormone Binding Globulin Previously Observed Antibody Staining Patterns
| Sex Hormone Binding Globulin General Information | |
|---|---|
| Alternate Names | |
| Sex hormone-binding globulin, SHBG, sex steroid-binding globulin, SSBG | |
| Molecular Weight | |
| 45kDa | |
| Chromosomal Location | |
| 17p13.1 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | SHBG |
| Entrez Gene ID | 6462 |
| Ensemble Gene ID | ENSG00000129214 |
| RefSeq Protein Accession(s) | NP_001139751, NP_001139753, NP_001276045, NP_001139752, NP_001276043, NP_001031, NP_001276042, NP_001276044 |
| RefSeq mRNA Accession(s) | NM_001146281 NM_001146279, NM_001289113, NM_001146280, NM_001289114, NM_001289115, NM_001040, NM_001289116 |
| RefSeq Genomic Accession(s) | NC_000017, NG_011981, NC_018928 |
| UniProt ID(s) | B4DYU0, B0FWH2, P04278, I3L145, B0FWH8 |
| UniGene ID(s) | B4DYU0, B0FWH2, P04278, I3L145, B0FWH8 |
| HGNC ID(s) | 10839 |
| Cosmic ID(s) | SHBG |
| KEGG Gene ID(s) | hsa:6462 |
| PharmGKB ID(s) | PA35745 |
| General Description of Sex Hormone Binding Globulin. | |
| Recognizes a protein of 45kDa, identified as SHBG. It functions as an,rogen transport protein, but may also be involved in receptor-mediated processes. Each dimer binds one molecule of steroid. It is specific for 5-alpha-dihydrotestosterone, testosterone,, 17-beta-estradiol. SHBG regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration. In testis, it is synthesized by the Sertoli cells, secreted into the lumen of the seminiferous tubule, transported to the epididymis. | |
Limitations and Warranty
enQuire Bio’s Sex Hormone Binding Globulin Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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