Anti-SUMO-1 Antibody Clone SUMO1/1188

Observed Subcellular, Organelle Specific Staining Data:

Variations in SUMO-1 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the adrenal gland, hematopoietic cells in the bone marrow, adipocytes in breast, respiratory epithelial cells in the bronchus, glandular cells in the duodenum, endometrium, epididymis, fallopian tube and gallbladder, macrophages in lung, pneumocytes in lung, respiratory epithelial cells in the nasopharynx, glandular cells in the parathyroid gland, decidual cells in the placenta, trophoblastic cells in the placenta, glandular cells in the rectum, myocytes in skeletal muscle, fibroblasts in skin, keratinocytes in skin, Langerhans in skin, melanocytes in skin, glandular cells in the small intestine, adipocytes in mesenchymal tissue, fibroblasts in mesenchymal tissue, cells in the seminiferous ducts in testis, germinal center cells in the tonsil, non-germinal center cells in the tonsil and urothelial cells in the urinary bladder. More moderate antibody staining intensity was present in glandular cells in the adrenal gland, hematopoietic cells in the bone marrow, adipocytes in breast, respiratory epithelial cells in the bronchus, glandular cells in the duodenum, endometrium, epididymis, fallopian tube and gallbladder, macrophages in lung, pneumocytes in lung, respiratory epithelial cells in the nasopharynx, glandular cells in the parathyroid gland, decidual cells in the placenta, trophoblastic cells in the placenta, glandular cells in the rectum, myocytes in skeletal muscle, fibroblasts in skin, keratinocytes in skin, Langerhans in skin, melanocytes in skin, glandular cells in the small intestine, adipocytes in mesenchymal tissue, fibroblasts in mesenchymal tissue, cells in the seminiferous ducts in testis, germinal center cells in the tonsil, non-germinal center cells in the tonsil and urothelial cells in the urinary bladder. Low, but measureable presence of SUMO-1 could be seen inglandular cells in the appendix, lymphoid tissue in appendix, glial cells in the caudate nucleus and cerebral cortex, bile duct cells in the liver and Leydig cells in the testis. We were unable to detect SUMO-1 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.