PDF DatasheetHuman Anti-CD10 (Membrane Metalloendopeptidase) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD10 (Membrane Metalloendopeptidase) Antibody Clone: MME/1870
Clone MME/1870 Host and Isotype: Mouse IgG2c, kappa
Anti-Human CD10 (Membrane Metalloendopeptidase) Positive Control Sample: Kidney, Prostate or Small Intestine
Cellular Localization of Antibody MME/1870 Staining: Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human CD10 protein fragment (aa297-483) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD10 (Membrane Metalloendopeptidase) Previously Observed Antibody Staining Patterns
| CD10 (Membrane Metalloendopeptidase) General Information | |
|---|---|
| Alternate Names | |
| Atriopeptidase; Common acute lymphocytic leukemia antigen (CALLA); Enkephalinase (EPN); gp100; Membrane metalloendopeptidase (MME); Neprilysin; Neutral endopeptidase (NEP); Skin fibroblast elastase (SFE) | |
| Molecular Weight | |
| 100kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 4311 |
| Entrez Gene ID | MME |
| UniProt ID(s) | P08473 |
| UniGene ID(s) | Hs307734 |
| COSMIC ID Link(s) | MME |
| KEGG Gene ID(s) | hsa:4311 |
| General Description of CD10 (Membrane Metalloendopeptidase). | |
| Recognizes a 100kDa glycoprotein, identified as CD10, also known as Common Acute Lymphocytic Leukemia Antigen (CALLA). It is a cell surface enzyme with neutral metalloendopeptidase activity, which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. | |
Limitations and Warranty
enQuire Bio’s product, CD10 (Membrane Metalloendopeptidase) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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