Human Anti-CD14 (Monocyte / Macrophage Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD14 (Monocyte / Macrophage Marker) Antibody Clone: LPSR/2397
Clone LPSR/2397 Host and Isotype: Mouse IgG2b, kappa
Anti-Human CD14 (Monocyte / Macrophage Marker) Positive Control Sample: THP-1 cells and human monocytes. Lymph nodes and tonsils.
Cellular Localization of Antibody LPSR/2397 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human CD14 protein (apprx. aa 25-148) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD14 (Monocyte / Macrophage Marker) Previously Observed Antibody Staining Patterns
CD14 (Monocyte / Macrophage Marker) General Information | |
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Alternate Names | |
Lipopolysaccharide receptor; LPS-R; LPSR; Mo2; Monocyte Differentiation Antigen 14; Myeloid cell-specific leucine-rich glycoprotein | |
Molecular Weight | |
55kDa | |
Chromosomal Location | |
Ships on blue ice. | |
Curated Database and Bioinformatic Data | |
Gene Symbol | 929 |
Entrez Gene ID | CD14 |
UniProt ID(s) | P08571 |
UniGene ID(s) | Hs163867 |
COSMIC ID Link(s) | CD14 |
KEGG Gene ID(s) | hsa:929 |
General Description of CD14 (Monocyte / Macrophage Marker). | |
Recognizes a protein of 55kDa, identified as CD14 (also known lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophage and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation. |
Limitations and Warranty
enQuire Bio’s product, CD14 (Monocyte / Macrophage Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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