PDF DatasheetHuman Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Antibody Clone: CR2/1953
Clone CR2/1953 Host and Isotype: Mouse IgG1, kappa
Anti-Human CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Positive Control Sample: WEHI-231 cells and Tonsil
Cellular Localization of Antibody CR2/1953 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 44-196) of human CR2 (CD21) protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) Previously Observed Antibody Staining Patterns
| CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| CD21; Complement C3d receptor (C3DR); Complement Receptor type 2 (CR2); CVID7; EBV receptor; EBV-R; Epstein-Barr virus receptor; EVBR; SLEB9 | |
| Molecular Weight | |
| 140kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 1380 |
| Entrez Gene ID | CR2 |
| UniProt ID(s) | P20023 |
| UniGene ID(s) | Hs445757 |
| COSMIC ID Link(s) | CR2 |
| KEGG Gene ID(s) | hsa:1380 |
| General Description of CD21 (Mature B-Cell & Follicular Dendritic Cell Marker). | |
| Recognizes a protein of 140kDa, which is identified as the complement receptor 2 (CR2) / CD21. This protein is expressed strongly on mature B cells, follicular dendritic cells and weakly on immature thymocytes and T lymphocytes. In B-cell ontogeny, CD21 appears after the pre-B-stage, is maintained during peripheral B-cell development and is lost upon terminal differentiation into plasma cells. CD21 expression is also gradually lost after stimulation of B cells in vitro. CD21 functions as receptor for C3d, C3dg and iC3b Complement components, for EBV and for IFNalpha. CD21 binds to CD23 and associates with CD19, CD81 and Leu13 to form a large signal-transduction complex involved in B cell activation. | |
Limitations and Warranty
enQuire Bio’s product, CD21 (Mature B-Cell & Follicular Dendritic Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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