Human Anti-CD25/ IL2RA (Activated Lymphocyte Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-CD25/ IL2RA (Activated Lymphocyte Marker) Antibody Clone: IL2RA/2395
Clone IL2RA/2395 Host and Isotype: Mouse IgG2b
Anti-Human CD25/ IL2RA (Activated Lymphocyte Marker) Positive Control Sample: PHA-stimulated human lymphocytes. Human lymph nodeor tonsil
Cellular Localization of Antibody IL2RA/2395 Staining: Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinantfragment of human IL2RA protein (apprx. aa 42-183) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD25/ IL2RA (Activated Lymphocyte Marker) Previously Observed Antibody Staining Patterns
CD25/ IL2RA (Activated Lymphocyte Marker) General Information | |
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Alternate Names | |
IL2 Receptor alpha; IL2R alpha chain; IL2R; IL2R subunit alpha IL2RA; Interleukin-2 receptor subunit alpha; Ly43; p55; p55 chain; T Cell Growth Factor Receptor; TAC antigen; TCGFR | |
Molecular Weight | |
55kDa | |
Chromosomal Location | |
Ships on blue ice. | |
Curated Database and Bioinformatic Data | |
Gene Symbol | 3559 |
Entrez Gene ID | IL2RA |
UniProt ID(s) | P01589 |
UniGene ID(s) | Hs231367 |
COSMIC ID Link(s) | IL2RA |
KEGG Gene ID(s) | hsa:3559 |
General Description of CD25/ IL2RA (Activated Lymphocyte Marker). | |
Recognizes a protein of 55kDa, identified as CD25.It is expressed on activated T- and B-cells and activated monocytes/macrophages.With respect to lymphomas, CD25 is present on malignant cells of Hodgkin s disease, HTLV-1+ adult T-cell leukemia, cutaneous T-cell lymphoma, and hair cell leukemia. Increased levels of soluble CD25 are observed in the leukemias/lymphomas and inflammatory/ autoimmune diseases. CD25 molecule alone appears to function as a low affinity receptor and associates with CD122 (IL-2R chain, p75) and CD132 (common chain) to form the high affinity IL-2 receptor complex.CD25 antibodies detect three epitope regions, A, B and C. This MAb recognizes the epitope B, which is located at residue 3-104 of CD25 and doe not block IL-2 binding to CD25. |
Limitations and Warranty
enQuire Bio’s product, CD25/ IL2RA (Activated Lymphocyte Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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