Human Anti-CD79b (B-Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-CD79b (B-Cell Marker) Antibody Clone: IGB/1844
Clone IGB/1844 Host and Isotype: Mouse IgG1, kappa
Anti-Human CD79b (B-Cell Marker) Positive Control Sample: Daudi or Ramos cells. Germinal center B-cells in a lymph node or tonsil.
Cellular Localization of Antibody IGB/1844 Staining: Cell surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human CD79b protein fragment (apprx. aa29-159) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
CD79b (B-Cell Marker) Previously Observed Antibody Staining Patterns
CD79b (B-Cell Marker) General Information | |
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Alternate Names | |
AGM6; B-cell antigen receptor complex-associated protein beta chain; B-cell-specific glycoprotein B29; B29; B29/Ig-beta/CD79b; CD79b; Ig-beta; IGB; Immunoglobulin-associated B29 protein | |
Molecular Weight | |
39kDa | |
Chromosomal Location | |
Ships on blue ice. | |
Curated Database and Bioinformatic Data | |
Gene Symbol | 974 |
Entrez Gene ID | CD79B |
UniProt ID(s) | P40259 |
UniGene ID(s) | Hs89575 |
COSMIC ID Link(s) | CD79B |
KEGG Gene ID(s) | hsa:974 |
General Description of CD79b (B-Cell Marker). | |
CD79 (also designated Ig α/Ig β) is a heterodimer composed of α chains, designated CD79A or MB-1, and β chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. |
Limitations and Warranty
enQuire Bio’s product, CD79b (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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