PDF DatasheetHuman Anti-Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-Cytokeratin 6A (KRT6A) (Basal Cell Marker) Antibody Clone: KRT6A/2368
Clone KRT6A/2368 Host and Isotype: Mouse IgG2a, kappa
Anti-Human Cytokeratin 6A (KRT6A) (Basal Cell Marker) Positive Control Sample: Tonsil or Basal Cell Carcinoma (BCC)
Cellular Localization of Antibody KRT6A/2368 Staining: Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human Cytokeratin 6A (KRT6A) protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Cytokeratin 6A (KRT6A) (Basal Cell Marker) Previously Observed Antibody Staining Patterns
| Cytokeratin 6A (KRT6A) (Basal Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| 58kDa Cytokeratin; CK5; Cytokeratin-5; DDD1; Epidermolysis Bullosa Simplex 2 (EBS2); Keratin 5; Keratin, Type II Cytoskeletal 5; Keratin-5; KRT5; Type-II Cytoskeletal 5; Type-II keratin Kb5 | |
| Molecular Weight | |
| 56kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 3853 |
| Entrez Gene ID | KRT6A |
| UniProt ID(s) | P02538 |
| UniGene ID(s) | Hs700779 |
| COSMIC ID Link(s) | KRT6A |
| KEGG Gene ID(s) | hsa:3853 |
| General Description of Cytokeratin 6A (KRT6A) (Basal Cell Marker). | |
| This MAb recognizes a protein of 56kDa, identified as cytokeratin 6A (KRT6A). In humans, multiple isoforms of Cytokeratin 6 (6A-6F), encoded by several highly homologous genes, have distinct tissue expression patterns. Cytokeratin 6A is the dominant form in epithelial tissue. Cytokeratin 6 and 16 are expressed in keratinocytes, which are undergoing rapid turnover in the suprabasal region (also known as hyper-proliferation-related keratins). Cytokeratin 6 is found in hair follicles, suprabasal cells of a variety of internal stratified epithelia, in epidermis, in both normal and hyper-proliferative situations. Epidermal injury results in activation of keratinocytes, which express KRT6 and KRT16. KRT6 is strongly expressed in about 75% of head and neck squamous cell carcinomas.. | |
Limitations and Warranty
enQuire Bio’s product, Cytokeratin 6A (KRT6A) (Basal Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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