PDF DatasheetHuman Anti-Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody Product Attributes
Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Antibody Clone: ELN/1981
Clone ELN/1981 Host and Isotype: Mouse IgG1, kappa
Anti-Human Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Positive Control Sample: A549 or U-2197cells. Liver, Kidney, Lung or Intestine.
Cellular Localization of Antibody ELN/1981 Staining: Secreted and Extracellular Space
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human Elastin protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) Previously Observed Antibody Staining Patterns
| Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) General Information | |
|---|---|
| Alternate Names | |
| Elastin; ELN; SVAS; Tropoelastin; WBS; WS | |
| Molecular Weight | |
| 70kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 2006 |
| Entrez Gene ID | ELN |
| UniProt ID(s) | P15502 |
| UniGene ID(s) | Hs647061 |
| COSMIC ID Link(s) | ELN |
| KEGG Gene ID(s) | hsa:2006 |
| General Description of Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis). | |
| Elastin is a polymeric protein and is the main component of the extracellular matrix of arteries. It is synthesized and secreted as a soluble, single-chain protein (tropoelastin), which undergoes a number of post-translational modifications prior to its organization into an elastic fiber in the extracellular space. Elastin performs a regulatory function during arterial development by controlling proliferation of smooth muscle and stabilizing arterial structure. It imparts elasticity to the connective tissue. During aging, the elasticity of connective tissue is reduced because of the cross-linking of collagenous fibers with elastin. The abnormal accumulation of elastic tissue in blood vessels is found in atherosclerosis and hypertension. | |
Limitations and Warranty
enQuire Bio’s product, Elastin (ELN) (Marker of Arterial Stiffness and Atherosclerosis) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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