PDF DatasheetHuman Anti-GLUT-1 (Tumor Progression and Mesothelioma Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-GLUT-1 (Tumor Progression and Mesothelioma Marker) Antibody Clone: GLUT1/2476
Clone GLUT1/2476 Host and Isotype: Mouse IgG2b, kappa
Anti-Human GLUT-1 (Tumor Progression and Mesothelioma Marker) Positive Control Sample: MDA-MB-231 cells or erythrocytes. Mesothelioma or breast, colon and ovarian carcinoma.
Cellular Localization of Antibody GLUT1/2476 Staining: Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human GLUT1 protein (apprx. aa 203-305) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
GLUT-1 (Tumor Progression and Mesothelioma Marker) Previously Observed Antibody Staining Patterns
| GLUT-1 (Tumor Progression and Mesothelioma Marker) General Information | |
|---|---|
| Alternate Names | |
| Erythrocyte/hepatoma glucose transporter; Glucose transporter type-1; GLUT1; GLUT1DS; GLUTB; GT1; GTG1; Gtg3; HepG2 glucose transporter; PED; RATGTG1; Solute carrier family 2; Solute carrier family 2, facilitated glucose transporter member 1 (SLC2A1) | |
| Molecular Weight | |
| 55kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 6513 |
| Entrez Gene ID | SLC2A1 |
| UniProt ID(s) | P11166 |
| UniGene ID(s) | Hs473721 |
| COSMIC ID Link(s) | SLC2A1 |
| KEGG Gene ID(s) | hsa:6513 |
| General Description of GLUT-1 (Tumor Progression and Mesothelioma Marker). | |
| Recognizes a protein of 55kDa, which is identified as GLUT-1. Glucose transporters are integral membrane glycoproteins involved in transporting glucose into most cells. There are many types of glucose transport carrier proteins, designated as Glut-1 to Glut-12. Glut-1 is a major glucose transporter in the mammalian blood-brain barrier. It is expressed in high density on the membranes of human erythrocytes and the brain capillaries that comprise the blood-brain barrier. Glut-1 is expressed at variable levels in many human tissues. Overexpression of Glut-1 has been linked to tumor progression or poor survival of patients with carcinomas of the colon, breast, cervical, lung, bladder and mesothelioma. Glut-1 is a sensitive and specific marker for the differentiation of malignant mesothelioma (positive) from reactive mesothelium (negative). | |
Limitations and Warranty
enQuire Bio’s product, GLUT-1 (Tumor Progression and Mesothelioma Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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