Human Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody Product Attributes
Species: Human
Tested Applications: ELISA.
Clonality: Monoclonal
Anti-IL3RA / CD123 (Acute Myeloid Leukemia Marker) Antibody Clone: IL3RA/2065
Clone IL3RA/2065 Host and Isotype: Mouse IgG2a, kappa
Anti-Human IL3RA / CD123 (Acute Myeloid Leukemia Marker) Positive Control Sample: THP-1, RPMI-8226 or HDLM-2 cells. Tonsil, Lymph Node or Stomach
Cellular Localization of Antibody IL3RA/2065 Staining: Cell Surface and Cytoplasmic
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human IL3RA protein fragment (apprx. aa 26-171) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
IL3RA / CD123 (Acute Myeloid Leukemia Marker) Previously Observed Antibody Staining Patterns
IL3RA / CD123 (Acute Myeloid Leukemia Marker) General Information | |
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Alternate Names | |
CD123; hIL3Ra; IL-3R-alpha; IL-3RA; IL3RAX; IL3RAY; IL3RX; IL3RY; Interleukin-3 Receptor, alpha; Interleukin3 receptor; Interleukin3 receptor, Y-chromosomal | |
Molecular Weight | |
~70kDa | |
Chromosomal Location | |
Ships on blue ice. | |
Curated Database and Bioinformatic Data | |
Gene Symbol | 3563 |
Entrez Gene ID | IL3RA |
UniProt ID(s) | P26951 |
UniGene ID(s) | Hs632790 |
COSMIC ID Link(s) | IL3RA |
KEGG Gene ID(s) | hsa:3563 |
General Description of IL3RA / CD123 (Acute Myeloid Leukemia Marker). | |
CD123 is an interleukin 3 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL3 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL3. This gene and the gene encoding the colony stimulating factor 2 receptor alpha chain (CSF2RA) form a cytokine receptor gene cluster in a X-Y pseudo-autosomal region on chromosomes X or Y. |
Limitations and Warranty
enQuire Bio’s product, IL3RA / CD123 (Acute Myeloid Leukemia Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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