PDF DatasheetHuman Anti-Kappa Light Chain (B-Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: Flow, IF, WB, IHC.
Clonality: Monoclonal
Anti-Kappa Light Chain (B-Cell Marker) Antibody Clone: rKLC264
Clone rKLC264 Host and Isotype: Mouse IgG1
Anti-Human Kappa Light Chain (B-Cell Marker) Positive Control Sample: 293T, Raji or hPBL cells. Tonsil or Spleen
Cellular Localization of Antibody rKLC264 Staining: Cell Surface, cytoplasmic and secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human Ig kappa chain
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Kappa Light Chain (B-Cell Marker) Previously Observed Antibody Staining Patterns
| Kappa Light Chain (B-Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| HCAK1; Ig Kappa Chain C Region; IGKC; Immunoglobulin KM | |
| Molecular Weight | |
| ~22.5kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 3514 |
| Entrez Gene ID | IGKC |
| UniProt ID(s) | P01601 & P01834 |
| UniGene ID(s) | Hs449609 |
| COSMIC ID Link(s) | IGKC |
| KEGG Gene ID(s) | hsa:3514 |
| General Description of Kappa Light Chain (B-Cell Marker). | |
| This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant. | |
Limitations and Warranty
enQuire Bio’s product, Kappa Light Chain (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
There are no reviews yet.