Human Anti-MyoD1 (Rhabdomyosarcoma Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-MyoD1 (Rhabdomyosarcoma Marker) Antibody Clone: rMYD712
Clone rMYD712 Host and Isotype: Mouse IgG1, kappa
Anti-Human MyoD1 (Rhabdomyosarcoma Marker) Positive Control Sample: Rhabdomyosarcoma
Cellular Localization of Antibody rMYD712 Staining: Nuclear. Only nuclear staining should be considered as evidence of skeletal muscle differentiation.
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human MyoD1 protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
MyoD1 (Rhabdomyosarcoma Marker) Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-MYOD1 antibody staining is expected to be primarily localized to the nuclear bodies and nucleoplasm.
MyoD1 (Rhabdomyosarcoma Marker) General Information | |
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Alternate Names | |
bHLHc1, Class C basic helix-loop-helix protein 1, Myoblast determination protein 1, Myogenic differentiation 1, Myogenic factor 3 (Myf-3), Myogenin D1, PUM | |
Molecular Weight | |
45kDa | |
Chromosomal Location | |
Ships on blue ice. | |
Curated Database and Bioinformatic Data | |
Gene Symbol | 4654 |
Entrez Gene ID | MYOD1 |
UniProt ID(s) | P15172 |
UniGene ID(s) | Hs181768 |
COSMIC ID Link(s) | MYOD1 |
KEGG Gene ID(s) | hsa:4654 |
General Description of MyoD1 (Rhabdomyosarcoma Marker). | |
Recognizes a phosphor-protein of 45kDa, identified as MyoD1. This MAb does not cross react with myogenin, Myf5, or Myf6. Antibody to MyoD1 labels the nuclei of myoblasts in developing muscle tissues. MyoD1 is not detected in normal adult tissue, but is highly expressed in the tumor cell nuclei of rhabdomyosarcomas. Occasionally nuclear expression of MyoD1 is seen in ectomesenchymoma and a subset of Wilm s tumors. Weak cytoplasmic staining is observed in several non-muscle tissues, including glandular epithelium and also in rhabdomyosarcomas, neuroblastomas, Ewing s sarcomas and alveolar soft part sarcomas. |
Limitations and Warranty
enQuire Bio’s product, MyoD1 (Rhabdomyosarcoma Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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