PDF DatasheetHuman Anti-PAX5 / BSAP (Early B-Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IP, WB, IHC.
Clonality: Monoclonal
Anti-PAX5 / BSAP (Early B-Cell Marker) Antibody Clone: PCRP-PAX5-1B7
Clone PCRP-PAX5-1B7 Host and Isotype: Mouse IgG1
Anti-Human PAX5 / BSAP (Early B-Cell Marker) Positive Control Sample: Raji, DAUDI or Ramos Cells. Tonsil, spleen, Lymph Node or Colon Carcinoma.
Cellular Localization of Antibody PCRP-PAX5-1B7 Staining: Nucleus
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant full-length human PAX5 protein
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
PAX5 / BSAP (Early B-Cell Marker) Previously Observed Antibody Staining Patterns
| PAX5 / BSAP (Early B-Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| B cell lineage specific activator; BSAP; EBB-1; KLP; Paired box 5 | |
| Molecular Weight | |
| 42kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 5079 |
| Entrez Gene ID | PAX5 |
| UniProt ID(s) | Q02548 |
| UniGene ID(s) | Hs654464 |
| COSMIC ID Link(s) | PAX5 |
| KEGG Gene ID(s) | hsa:5079 |
| General Description of PAX5 / BSAP (Early B-Cell Marker). | |
| The specificity of this monoclonal antibody to its intended target was validated by HuProtTM Array, containing more than 19,000, full-length human proteins. The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding domain, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis; therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis. | |
Limitations and Warranty
enQuire Bio’s product, PAX5 / BSAP (Early B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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