PDF DatasheetMulti Species Exendin 4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant Exendin 4 based upon sequence from Multi Species
Host: QP10593 protein expressed in E. Coli.
Available Tags: Untagged
Protein Construction: A cDNA sequence encoding the sequence of Exendin 4 was constructred and used to recombinantly synthesize the protein.
Recommended Applications: Bioactive
Application Notes
Recommended Reconstitution Instructions: It is recommended to reconstitute the lyophilized Exendin Recombinant in sterile 18MΩ.cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Bioactivity Data: 1. Regulates Glucose levels rapidly2. Reduces Insulin resistence 3. Reduces Glucagon4. Reduces HbA1c5. Stimulates beta cell growth which stimulates insulin production.
Amino Acid Sequence: The sequence determined and was found to be His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Met-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser
Purity: Greater than 95.0% as determined by:(a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Endotoxin Levels: < 1.0 EU per ug protein as determined by the LAL method.
Buffer: The Exendin-4 peptide was lyophilized after extensive dialyses against 20mM PBS and contains 4% mannitol.
Storage Conditions: Lyophilized Exendin Recombinant although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution Exendin-4 should be stored at 4°C between 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Physical Appearance: Sterile Filtered White lyophilized (freeze-dried) powder.
| Recombinant Multi Species Exendin 4 General Information | |
|---|---|
| Alternate Names | |
| Exenatide. | |
| Molecular Weight | |
| 4.2 kDa | |
| Curated Database and Bioinformatic Data | |
| UniProt ID(s) | P26349 |
| General Description of Recombinant Multi Species Exendin 4. | |
| Exendin-4 Recombinant is a novel 39-amino acids peptide having a molecular mass of 4186.7 Dalton, which shares 53%, sequence homology with GLP-17-36 amide and interacts with the same membrane receptor. The Exendin-4 is purified by using an optimized multi-step FPLC method for maximum separation from contaminants. | |
Limitations and Performance Guarantee
enQuire Bio’s products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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