PDF DatasheetHuman Anti-Renalase (Renal Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-Renalase (Renal Cell Marker) Antibody Clone: RNLS/1940
Clone RNLS/1940 Host and Isotype: Mouse IgG2b
Anti-Human Renalase (Renal Cell Marker) Positive Control Sample: 293T Cells. Heart or Kidney
Cellular Localization of Antibody RNLS/1940 Staining: Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human RNLS protein fragment (apprx. aa 34-235) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Renalase (Renal Cell Marker) Previously Observed Antibody Staining Patterns
| Renalase (Renal Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| Chromosome 10 open reading frame 59; MAO C; MAO-C; Monoamine oxidase-C; Renalase; Renalase FAD dependent amine oxidase; RNLS | |
| Molecular Weight | |
| 38kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 55328 |
| Entrez Gene ID | RNLS |
| UniProt ID(s) | Q5VYX0 |
| UniGene ID(s) | Hs149849 |
| COSMIC ID Link(s) | RNLS |
| KEGG Gene ID(s) | hsa:55328 |
| General Description of Renalase (Renal Cell Marker). | |
| Renalase is a 342 amino acid FAD-dependent amine oxidase that is highly expressed in kidney and is expressed at a lower level in heart, skeletal muscle and small intestine. Renalase is secreted in the blood by the kidney and it is thought to regulate cardiac function and systemic blood pressure. It is also suggested that Renalase functions as a hormone that metabolizes circulating catecholamines, which have an active role in the sympathetic and parasympathetic nervous systems. Individuals with chronic kidney disease and end-stage renal disease have markedly reduced levels of plasma Renalase than healthy individuals. Infusion of Renalase in animal models causes decrease in heart rate, cardiac contractility and blood pressure. Two isoforms of Renalase exist due to alternative splicing events. | |
Limitations and Warranty
enQuire Bio’s product, Renalase (Renal Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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