PDF DatasheetHuman Anti-Spectrin Alpha 1 (Erythrocyte Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC, ELISA.
Clonality: Monoclonal
Anti-Spectrin Alpha 1 (Erythrocyte Marker) Antibody Clone: SPTA1/1832
Clone SPTA1/1832 Host and Isotype: Mouse IgG2b, kappa
Anti-Human Spectrin Alpha 1 (Erythrocyte Marker) Positive Control Sample: Jurkat cells. Placenta or Tonsil.
Cellular Localization of Antibody SPTA1/1832 Staining: Cytoplasmic and Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant human SPTA fragment (apprx. aa356-475) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
Spectrin Alpha 1 (Erythrocyte Marker) Previously Observed Antibody Staining Patterns
| Spectrin Alpha 1 (Erythrocyte Marker) General Information | |
|---|---|
| Alternate Names | |
| Alpha I spectrin; Elliptocytosis 2 (EL2); Erythrocyte alpha spectrin; Erythroid alpha-spectrin; HPP; HS3; Spectrin alpha erythrocytic 1; SPH3; SPTA1 | |
| Molecular Weight | |
| 240kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 6708 |
| Entrez Gene ID | SPTA1 |
| UniProt ID(s) | P02549 |
| UniGene ID(s) | Hs119825 |
| COSMIC ID Link(s) | SPTA1 |
| KEGG Gene ID(s) | hsa:6708 |
| General Description of Spectrin Alpha 1 (Erythrocyte Marker). | |
| Spectrin is an actin crosslinking and molecular scaffold protein that links the plasma membrane to the actin cytoskeleton, and functions in the determination of cell shape, arrangement of transmembrane proteins, and organization of organelles. Spectrins function as membrane organizers and stabilizers, composed of non-homologous α and β chains, which aggregate side-to-side in an anti-parallel fashion to form dimers, tetramers and higher polymers. Spectrin α I and spectrin β I are present in erythrocytes, whereas spectrin α II (also designated fodrin α) and spectrin β II (also designated fodrin β) are present in other somatic cells. The spectrin tetramers in erythrocytes act as barriers to lateral diffusion, but spectrin dimers seem to lack this function. | |
Limitations and Warranty
enQuire Bio’s product, Spectrin Alpha 1 (Erythrocyte Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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