PDF DatasheetHuman Anti-StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Antibody Product Attributes
Species: Human
Tested Applications: IHC.
Clonality: Monoclonal
Anti-StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Antibody Clone: STAR/2154
Clone STAR/2154 Host and Isotype: Mouse IgG1, kappa
Anti-Human StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Positive Control Sample: K-562 cells. Adrenal or Testicular Carcinoma
Cellular Localization of Antibody STAR/2154 Staining: Cytoplasmic (Mitochondria)
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment (apprx. aa 39-108) of human STAR protein (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.
StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) Previously Observed Antibody Staining Patterns
| StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) General Information | |
|---|---|
| Alternate Names | |
| Cholesterol trafficker; Luteinizing hormone induced protein; Mitochondrial steroid acute regulatory protein; StAR; StAR related lipid transfer (START) domain containing 1; StARD1; START domain-containing protein 1; Steroid acute regulatory protein; Steroidogenic acute regulator (STAR); Steroidogenic acute regulatory protein mitochondrial | |
| Molecular Weight | |
| 30kDa | |
| Chromosomal Location | |
| Ships on blue ice. | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | 6770 |
| Entrez Gene ID | STAR |
| UniProt ID(s) | P49675 |
| UniGene ID(s) | Hs521535 |
| COSMIC ID Link(s) | STAR |
| KEGG Gene ID(s) | hsa:6770 |
| General Description of StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker). | |
| Steroidogenic Acute Regulatory Protein (STAR) controls the rate-limiting step of steroidegenesis by translocating cholesterol from the outer mitochondrial membrane to the inner membrane where it is later cleaved to pregnenolone. It is primarily present in steroid-producing cells, including Leydig cells in the testis, theca cells and luteal cells in the ovary and adrenal cells in the adrenal cortex. Due to low levels of pregnenolone, seminomas and Leydig cell tumors display no specific STAR staining. Therefore, STAR antibody may assist in differentiating sex cord stromal tumors (SCST), seminomas and embryonal carcinomas. | |
Limitations and Warranty
enQuire Bio’s product, StAR (Steroidogenic Acute Regulator) (Leydig Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.
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