Western Blot Analysis of human HeLa Cell Lysate using TLE1 Mouse Monoclonal Antibody (TLE1/2051).

Analysis of Protein Array containing more than 19,000 full-length human proteins using TLE1 Mouse Monoclonal Antibody (TLE1/2051). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

SDS-PAGE Analysis Purified TLE1 Mouse Monoclonal Antibody (TLE1/2051).Confirmation of Integrity and Purity of Antibody.

TLE1 (Synovial Sarcoma Marker) Ultraspecific Antibody
Tested against >20,000 Human Proteins

Name: TLE1 (Synovial Sarcoma Marker) Ultraspecific Antibody <p style="font-size:small">Tested against &gt;20,000 Human Proteins</p>
SKU: 7088-MSM1-P0
Availability: InStock

$ 228.00 – $ 488.00

SKU: 7088-MSM1
Species: Human
Tested Applications: WB, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2a, kappa
Mass Spec Validated?: Not MS Validated

Size

Tag

Clear

SKU: 7088-MSM1-P0 Categories: Antibody, Human, IgG2a, IHC, kappa, Mouse, Not MS Validated, Ultraspecific Antibodies, Unconjugated, WB Tag: TLE1 (Synovial Sarcoma Marker)

PDF Datasheet

Human Anti-TLE1 (Synovial Sarcoma Marker) Antibody Product Attributes

Species: Human

Tested Applications: WB, IHC.

Clonality: Monoclonal

Anti-TLE1 (Synovial Sarcoma Marker) Antibody Clone: TLE1/2051

Clone TLE1/2051 Host and Isotype: Mouse IgG2a, kappa

Anti-Human TLE1 (Synovial Sarcoma Marker) Positive Control Sample: HeLa, HepG2 or Jurkat cells. Endometrium Carcinoma or Sarcomas

Cellular Localization of Antibody TLE1/2051 Staining: Nuclear

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.

Antibody Concentration: 200 ug/ml

Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.

Immunogen: Recombinant human TLE1 fragment (aa 175-338) (Please call for additional information.)

Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

TLE1 (Synovial Sarcoma Marker) Previously Observed Antibody Staining Patterns

TLE1 (Synovial Sarcoma Marker) General Information
Alternate Names
Enhancer of split groucho 1 (ESG1); Enhancer of split groucho-like protein 1; GRG1; TLE1; Transducin like enhancer of split 1; Transducin-like enhancer protein 1
Molecular Weight
83kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol	7088
Entrez Gene ID	TLE1
UniProt ID(s)	Q04724
UniGene ID(s)	Hs197320; 689805
COSMIC ID Link(s)	TLE1
KEGG Gene ID(s)	hsa:7088
General Description of TLE1 (Synovial Sarcoma Marker).
Key players in the Notch pathway are the TLE genes, which are human homologs of the Drosophila groucho gene. Groucho is a transcriptional repressor that plays a key role in neurogenesis, segmentation and sex determination. Transducin-like enhancer protein 1 (TLE1) is a protein that is encoded by the TLE1 gene and is involved in control of hematopoiesis, neuronal, and terminal epithelial differentiation. Positive immunohistochemical nuclear staining with anti-TLE-1 has been shown to be a useful addition to an IHC panel when differentiating synovial sarcoma from other soft tissue malignancies.

Limitations and Warranty

enQuire Bio’s product, TLE1 (Synovial Sarcoma Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

Size	20 ug, 100 ug
Tag	Unconjugated
Buffer and Stabilizer	10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Product Type	Antibody
Host	Mouse
Isotype	IgG2a, kappa
Applications	WB
Species	Human
Mass Spec Validated?	Not MS Validated

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TLE1 (Synovial Sarcoma Marker) Ultraspecific Antibody Tested against >20,000 Human Proteins

Human Anti-TLE1 (Synovial Sarcoma Marker) Antibody Product Attributes

TLE1 (Synovial Sarcoma Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

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