Data from SDS-PAGE analysis of Anti-Ubiquitin antibody (Clone UBB/1748). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.

Formalin-fixed, paraffin-embedded human Brain stained with Ubiquitin Mouse Monoclonal Antibody (UBB/1748).

Ubiquitin (Autophagy Marker) Ultraspecific Antibody
Tested against >20,000 Human Proteins

Name: Ubiquitin (Autophagy Marker) Ultraspecific Antibody <p style="font-size:small">Tested against &gt;20,000 Human Proteins</p>
SKU: 7314-MSM1-P0
Availability: InStock

$ 228.00 – $ 488.00

SKU: 7314-MSM1
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2c, kappa
Mass Spec Validated?: Not MS Validated

Size

Tag

Clear

SKU: 7314-MSM1-P0 Categories: Antibody, Human, IgG2c, IHC, kappa, Mouse, Not MS Validated, Ultraspecific Antibodies, Unconjugated Tag: Ubiquitin (Autophagy Marker)

PDF Datasheet

Human Anti-Ubiquitin (Autophagy Marker) Antibody Product Attributes

Species: Human

Tested Applications: IHC and western blot.

Clonality: Monoclonal

Anti-Ubiquitin (Autophagy Marker) Antibody Clone: UBB/1748

Clone UBB/1748 Host and Isotype: Mouse IgG2c, kappa

Anti-Human Ubiquitin (Autophagy Marker) Positive Control Sample: HeLa or Jurkat cells. Alzheimer s Brain

Cellular Localization of Antibody UBB/1748 Staining: Cell Surface, Cytoplasmic and Nuclear

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.

Antibody Concentration: 200 ug/ml

Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.

Immunogen: Recombinant fragment of human Ubiquitin protein (apprx. aa 1-119) (Please call for additional information.)

Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Ubiquitin (Autophagy Marker) General Information
Alternate Names
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
Molecular Weight
9kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol	7314
Entrez Gene ID	UBB
UniProt ID(s)	P0CG47; P0CG48; P62979; P62987 and P62988
UniGene ID(s)	Hs356190 and 520348
COSMIC ID Link(s)	UBB
KEGG Gene ID(s)	hsa:7314
General Description of Ubiquitin (Autophagy Marker).
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer’s disease, Lewy bodies seen in Parkinson’s disease, and Pick bodies found in Pick’s disease etc.

Limitations and Warranty

enQuire Bio’s product, Ubiquitin (Autophagy Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

Size	20 ug, 100 ug
Tag	Unconjugated
Buffer and Stabilizer	10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Product Type	Antibody
Host	Mouse
Isotype	IgG2c, kappa
Applications	IHC, WB
Species	Human
Mass Spec Validated?	Not MS Validated

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Ubiquitin (Autophagy Marker) Ultraspecific Antibody Tested against >20,000 Human Proteins

Human Anti-Ubiquitin (Autophagy Marker) Antibody Product Attributes

Limitations and Warranty

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