.jpg "VEGI IHC human Colon Carcinoma (VEGI 1283)")
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Human Anti-VEGI Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-VEGI Antibody Clone: VEGI/1283
Clone VEGI/1283 Host and Isotype: Mouse IgG1 kappa
Anti-Human VEGI Positive Control Sample: Endothelial cells. Colon, intestine, placenta, lung, liver, kidney, pancreas, spleen and prostate.
Cellular Localization of Antibody Secreted and Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human full-length VEGI fragment
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
VEGI Previously Observed Antibody Staining Patterns
Observed Subcellular, Organelle Specific Staining Data:
Anti-TNFSF15 antibody staining is expected to be primarily localized to the cytosol, nuclear membrane and nucleus.Observed Antibody Staining Data By Tissue Type:
Variations in VEGI antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of VEGI could be seen inglandular cells in the breast, myoepithelial cells in the breast, neuronal cells in the caudate nucleus, endothelial cells in the cerebral cortex, squamous epithelial cells in the cervix, uterine, endothelial cells in the colon, cells in the endometrial stroma in endometrium, cells in the glomeruli in kidney, bile duct cells in the liver, hepatocytes in liver, pneumocytes in lung, squamous epithelial cells in the oral mucosa, exocrine glandular cells in the pancreas, glandular cells in the salivary gland, keratinocytes in skin, melanocytes in skin, fibroblasts in mesenchymal tissue, germinal center cells in the tonsil, non-germinal center cells in the tonsil and squamous epithelial cells in the tonsil and vagina. We were unable to detect VEGI in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.Observed Antibody Staining Data By Tissue Disease Status:
Tissues from cancer patients, for instance, have their own distinct pattern of VEGI expression as measured by anti-VEGI antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.| Sample Type | breast cancer | carcinoid | cervical cancer | colorectal cancer | endometrial cancer | glioma | head and neck cancer | liver cancer | lung cancer | lymphoma | melanoma | ovarian cancer | pancreatic cancer | prostate cancer | renal cancer | skin cancer | stomach cancer | testicular cancer | thyroid cancer | urothelial cancer |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Signal Intensity | + | + | + | + | ++ | + | + | + | + | - | + | ++ | + | + | - | + | + | - | ++ | + |
| TNFSF15 Variability | + | ++ | ++ | ++ | ++ | +++ | ++ | ++ | ++ | ++ | ++ | ++ | ++ | +++ | ++ | ++ | ++ | ++ | ++ | ++ |
Limitations and Warranty
enQuire Bio's VEGI Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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