C57Bl/6 splenocytes were stained with FITC Mouse Anti-CD3e  and 0.125 ug APC Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.125 ug APC Mouse IgG2a isotype control (left panel).
C57Bl/6 splenocytes were stained with FITC Mouse Anti-CD3e  and 0.125 ug APC Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.125 ug APC Mouse IgG2a isotype control (left panel).C57Bl/6 splenocytes were stained with 0.5 ug FITC Mouse Anti-NK1.1 (CD161) (QAB78) (solid line) or 0.5 ug FITC Mouse IgG2a isotype control (dashed line). Flow Cytometry Data from 10,000 events.C57Bl/6 splenocytes were stained with FITC Mouse Anti-CD3e  and 0.25 ug PerCP-Cy5.5 Mouse Anti-NK1.1 .C57Bl/6 splenocytes were stained with APC Mouse Anti-CD3e  and 0.5 ug PE Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.5 ug PE Mouse IgG2a isotype control (left panel).C57Bl/6 splenocytes were stained with APC Mouse Anti-CD3e  and 0.5 ug PE-Cy7 Mouse Anti-NK1.1 .C57Bl/6 splenocytes were stained with PE Mouse Anti-CD3e  and 0.125 ug Qfluor™ 710 Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.125 ug Qfluor™ 710 Mouse IgG2a isotype control (left panel).C57Bl/6 splenocytes were stained with FITC Mouse Anti-CD3e  and 0.125 ug APC Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.125 ug APC Mouse IgG2a isotype control (left panel).C57Bl/6 splenocytes were stained with 0.5 ug FITC Mouse Anti-NK1.1 (CD161) (QAB78) (solid line) or 0.5 ug FITC Mouse IgG2a isotype control (dashed line). Flow Cytometry Data from 10,000 events.C57Bl/6 splenocytes were stained with FITC Mouse Anti-CD3e  and 0.25 ug PerCP-Cy5.5 Mouse Anti-NK1.1 .C57Bl/6 splenocytes were stained with APC Mouse Anti-CD3e  and 0.5 ug PE Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.5 ug PE Mouse IgG2a isotype control (left panel).C57Bl/6 splenocytes were stained with APC Mouse Anti-CD3e  and 0.5 ug PE-Cy7 Mouse Anti-NK1.1 .C57Bl/6 splenocytes were stained with PE Mouse Anti-CD3e  and 0.125 ug Qfluor™ 710 Mouse Anti-NK1.1 (CD161) (QAB78) (right panel) or 0.125 ug Qfluor™ 710 Mouse IgG2a isotype control (left panel).

Anti-CD161 Antibody [PK136]

$ 49.00$ 249.00
Please Select Product Options Below To View The Catalog Number.

SKU: QAB78
Species: Mouse
Tested Applications: Flow Cytometry
Available Conjugates: Biotin ;Unconjugated ;APC ;FITC ;PerCP-Cy5.5 ;PE ;PE-Cy7 ;Qfluor 710
Isotype: Mouse IgG2a kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
QAB78-B-25ug Size: 25 ug, Tag: Biotin $ 49.00
QAB78-100ug Size: 100 ug, Tag: Unconjugated $ 79.00
QAB78-APC-100ug Size: 100 ug, Tag: APC $ 229.00
QAB78-APC-25ug Size: 25 ug, Tag: APC $ 79.00
QAB78-B-100ug Size: 100 ug, Tag: Biotin $ 119.00
QAB78-B-500ug Size: 500 ug, Tag: Biotin $ 199.00
QAB78-F-100ug Size: 100 ug, Tag: FITC $ 139.00
QAB78-F-25ug Size: 25 ug, Tag: FITC $ 49.00
QAB78-F-500ug Size: 500 ug, Tag: FITC $ 199.00
QAB78-PCP55-100ug Size: 100 ug, Tag: PerCP-Cy5.5 $ 249.00
QAB78-PCP55-25ug Size: 25 ug, Tag: PerCP-Cy5.5 $ 79.00
QAB78-PE-100ug Size: 100 ug, Tag: PE $ 149.00
QAB78-PE-25ug Size: 25 ug, Tag: PE $ 49.00
QAB78-PE7-100ug Size: 100 ug, Tag: PE-Cy7 $ 239.00
QAB78-PE7-25ug Size: 25 ug, Tag: PE-Cy7 $ 99.00
QAB78-QF710-100ug Size: 100 ug, Tag: Qfluorâ„¢ 710 $ 189.00
QAB78-QF710-25ug Size: 25 ug, Tag: Qfluorâ„¢ 710 $ 79.00
QAB78-QF630-100ug Size: 100 tests, Tag: Qfluor™ 630 $ 159.00
Shipping Information
In Stock.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
Lot Number:

Expiration Date:

Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

Manufacture Date:

Purity:

Bioactivity (test results eg. IU/ml):


SKU: QAB78-B-25ug
Anti-CD161 General Information
Alternate Names
CD161, NKR-P1C, Ly-55
Curated Database and Bioinformatic Data
Gene SymbolKlrb1c
Entrez Gene ID17059
Ensemble Gene IDENSMUSG00000030325
RefSeq Protein Accession(s)NP_032553, NP_001153376
RefSeq mRNA Accession(s)NM_001159904, NM_008527
RefSeq Genomic Accession(s)NC_000072
UniProt ID(s)E9Q3U6, G3UZI0, P27814
UniGene ID(s)E9Q3U6, G3UZI0, P27814
Cosmic ID(s)Klrb1c
KEGG Gene ID(s)mmu:17059
General Description of Anti-CD161.
The PK136 antibody is specific for mouse NK1.1, a type II transmembrane lectin-like receptor and member of the killer cell lectin-like receptor (KLR) family. NK1.1 is prominently expressed on natural killer (NK) cells, and is correlated with NK cytotoxic effects toward virus-infected cells and tumor cells. NK1.1 is expressed on subsets of NKT cells in certain mouse strains (C57BL/6, FVB/N, and NZB), yet absent from others (AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129). Putative subsets of NK cells and their expression of NK1.1 antigen are of continuing interest, including NK1.1+/CD117+ (c-Kit) cells reported to be immunosuppressive for CD8+ T cells in a mechanism involving PD-1 and PD-L1 (Ehlers et al. 2012. Endocrinology. 10: 1247).The PK136 antibody may be used for detection of NK1.1 expression on mouse strains including CE, B6, NZB, C58, Ma/My, ST, SJL, and FVB. The antibody is reported to react with an epitope common to NKR-P1B and NKR-P1C alloantigenic forms of NK1.1 (Carlyle et al. 2006. J. Immunol. 176: 7511-7524).

Mouse Anti-Anti-CD161 Antibody Product Attributes

Species: Mouse
Tested Applications: Flow Cytometry.
Application Notes: See Product Datasheet for Recommended Dilution Range. Requires Experimental Optimization
Clonality: Monoclonal Antibody
Anti-Anti-CD161 Antibody Clone: PK136
Clone PK136 Host and Isotype: Mouse IgG2a kappa
Buffer and Stabilizer: 10 mM NaH2PO4, 150 mM NaCl, 0.09% NaN3, pH 7.2
Antibody Concentration: 0.5 mg/mL
Storage Conditions: 2-8C protected from light. Stable for 12 Months. Do Not Freeze.

Anti-CD161 Previously Observed Antibody Staining Patterns

Selected References

Krebs DL, Chehal MK, Sio A, Huntington ND, Da ML, Ziltener P, Inglese M, Kountouri N, Priatel JJ, Jones J, Tarlinton DM, Anderson GP, Hibbs ML, and Harder KW. 2012. J. Immunol. 188:5094-5105. (in vivo depletion)Lubinski JM, Lazear HM, Awasthi S, Wang F, and Friedman HM. 2011. J. Virol. 85(7): 3239-3249. (in vivo depletion)Diamond MS, Kinder M, Matsushita H, Mashayekhi M, Dunn GP, Archambault JM, Lee H, Arthur CD, White JM, Kalinke U, Murphy KM, and Schreiber RD. 2011. J. Exp. Med. 208: 1989-2003. (in vivo depletion)Awasthi A, Samarakoon A, Chu H, Kamalakannan R, Quilliam LA, Chrzanowska-Wodnicka M, White GC, and Malarkannan S. 2010. J. Exp. Med. 207: 1923-1938. (in vitro activation)Coudert JD, Scarpellino L, Gros F, Vivier E, and Held W. 2008 Blood. 111: 3571-3578. (Immunoprecipitation) Ljutic B, Carlyle JR, Filipp D, Nakagawa R, Julius M, and Zuniga-Pflucker JC. 2005. J. Immunol. 174: 4789-4796. (Immunoprecipitation) Kanwar JR, Shen W-P, Kanwar RK, Berg RW, and Krissansen GW. 2001. J. Natl. Cancer Inst. 93: 1541-1552. (Immunohistochemistry - frozen tissue, Immunofluorescence microscopy - frozen tissue, in vivo depletion)

Limitations and Warranty

enQuire Bio's Mouse Anti-CD161 Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

There are no reviews yet.

Be the first to review “Anti-CD161 Antibody [PK136]”

Your email address will not be published. Required fields are marked *

Share a Protocol (View Reviewed Protocols Below)

Protocol Title

Materials

Methods

Notes


  protocol submission gif
enQuire Bio, LLC   8420 S Continental Divide Rd, #202   Littleton, CO 80127
Chat: See lower right corner. | enquire@enquirebio.com | Fax: 1-720-897-3730
Customer Service Available M-F 8AM-6PM MST or 24/7 Via Email

Anti-CD161 Antibody [PK136]

https://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-APC-100ug-anti-Anti-CD161-antibody-10-300x146.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-B-100ug-anti-Anti-CD161-antibody-10-300x148.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-F-100ug-anti-Anti-CD161-antibody-10-300x288.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-PCP55-100ug-anti-Anti-CD161-antibody-10-300x156.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-PE-100ug-anti-Anti-CD161-antibody-10-300x145.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-PE7-100ug-anti-Anti-CD161-antibody-10-300x148.pnghttps://enquirebio.com/wp-content/uploads/2017/10/enQuire-Bio-QAB78-QF710-100ug-anti-Anti-CD161-antibody-10-300x150.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-APC-100ug-anti-Anti-CD161-antibody-9-300x146.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-F-100ug-anti-Anti-CD161-antibody-9-300x288.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-PCP55-100ug-anti-Anti-CD161-antibody-9-300x156.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-PE-100ug-anti-Anti-CD161-antibody-9-300x145.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-PE7-100ug-anti-Anti-CD161-antibody-9-300x148.pnghttps://enquirebio.com/wp-content/uploads/2017/11/enQuire-Bio-QAB78-QF710-100ug-anti-Anti-CD161-antibody-9-300x150.png