Formalin-fixed, paraffin-embedded human Tonsil stained withCD162 Monoclonal Antibody (PSGL1/161).
Formalin-fixed, paraffin-embedded human Tonsil stained withCD162 Monoclonal Antibody (PSGL1/161).

Anti-CD162 Antibody Clone PSGL1/1601

$ 199.00$ 459.00
Please Select Product Options Below To View The Catalog Number.

SKU: 6404-MSM2
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
6404-MSM2-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
6404-MSM2-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
6404-MSM2-P2 Size: 200 ug, Tag: Unconjugated $ 459.00
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SKU: 6404-MSM2-P0
CD162 General Information
Alternate Names
Selectin P ligand, SELPLG, CD162, cluster of differentiation 162, P Selectin Ligand
Molecular Weight
43-120kDa
Chromosomal Location
12q24
Curated Database and Bioinformatic Data
Gene SymbolSELPLG
Entrez Gene ID6404
Ensemble Gene IDENSG00000110876
RefSeq Protein Accession(s)NP_002997, NP_001193538
RefSeq mRNA Accession(s)NM_001206609, NM_003006
RefSeq Genomic Accession(s)NC_000012, NC_018923
UniProt ID(s)Q14242
UniGene ID(s)Q14242
HGNC ID(s)10722
Cosmic ID(s)SELPLG
KEGG Gene ID(s)hsa:6404
PharmGKB ID(s)PA35644
General Description of CD162.
CD162 glycoprotein functions as a high affinity counter-receptor for the cell adhesion molecules P-, E- and L- selectin expressed on myeloid cells and stimulated T lymphocytes. As such, this protein plays a critical role in leukocyte trafficking during inflammation by tethering of leukocytes to activated platelets or endothelia expressing selectins. This protein requires two post-translational modifications, tyrosine sulfation and the addition of the sialyl Lewis x tetrasaccharide (sLex) to its O-linked glycans, for its high-affinity binding activity. Aberrant expression of this gene and polymorphisms in this gene are associated with defects in the innate and adaptive immune response.

Human Anti-CD162 Antibody Product Attributes

Species: Human
Tested Applications: Immunohistochemistry (IHC).
Clonality: Monoclonal
Anti-CD162 Antibody Clone: PSGL1/1601
Clone PSGL1/1601 Host and Isotype: Mouse IgG1
Anti-Human CD162 Positive Control Sample: Jurkat cells. Tonsil or Spleen
Cellular Localization of Antibody Cell Surface
Buffer and Stabilizer: 10mM PBS with 0.05% BSA and 0.05% Azide
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant human full-length SELPLG (CD162) protein
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

CD162 Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in CD162 antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. Low, but measureable presence of CD162 could be seen inlymphoid tissue in appendix, hematopoietic cells in the bone marrow and germinal center cells in the tonsil. We were unable to detect CD162 in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Limitations and Warranty

enQuire Bio's CD162 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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Anti-CD162 Antibody Clone PSGL1/1601

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