Formalin-fixed, paraffin-embedded human Tonsil stained with CD2 Monoclonal Antibody (L26)

Anti-CD20 / MS4A1 Antibody Clone L26

Name: Anti-CD20 / MS4A1 Antibody Clone L26
Brand: enQuire Bio
Price: 329 USD
Availability: InStock

$ 368.00

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SKU: 931-MSM2
Species: Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-)
Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG2a kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
931-MSM2-CS1	Size: 0.5 ml, Tag: Unconjugated

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In Stock.

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Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 931-MSM2-CS1

CD20 / MS4A1 General Information
Alternate Names
B-lymphocyte antigen CD20, CD20, Cluster of Differentiation 20
Molecular Weight
33-37kDa
Chromosomal Location
11q12.2
Curated Database and Bioinformatic Data
Gene Symbol	MS4A1
Entrez Gene ID	931
Ensemble Gene ID	ENSG00000156738
RefSeq Protein Accession(s)	NP_068769, NP_690605
RefSeq mRNA Accession(s)	NM_152866, NM_021950
RefSeq Genomic Accession(s)	NG_023388, NC_018922, NC_000011
UniProt ID(s)	P11836, A0A024R507
UniGene ID(s)	P11836, A0A024R507
HGNC ID(s)	7315
Cosmic ID(s)	MS4A1
KEGG Gene ID(s)	hsa:931
PharmGKB ID(s)	PA31111
General Description of CD20 / MS4A1.
Recognizes a protein of 30-33kDa, which is identified as CD20. Its epitope is located in the cytoplasmic domain of CD20, was, therefore, ascribed as CD20cy in the 5th Workshop. CD20 is a non-Ig differentiation antigen of B-cells, its expression is restricted to normal, neoplastic B-cells, being absent from all other leukocytes, tissues. CD20 is expressed by pre B-cells, persists during all stages of B-cell maturation but is lost upon terminal differentiation into plasma cells. This MAb can be used for immunophenotyping of leukemia, malignant cells, B lymphocyte detection in peripheral blood, B cell localization in tissues. It reacts with the majority of B-cells present in peripheral blood, lymphoid tissues, their derived lymphomas. In lymphoid tissue, germinal center blasts, B-immunoblasts are particularly reactive. It is a reliable antibody for ascribing a B-cell phenotype in known lymphoid tissues. Rarely, CD20-positive T-cell lymphomas have been reported. Reactivity has also been noted with Reed-Sternberg cells in cases of Hodgkins disease, particularly of lymphocyte predominant type.

Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-) Anti-CD20 / MS4A1 Antibody Product Attributes

Species: Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-)

Tested Applications: Flow Cytometry, Immunofluorescence, Immunohistochemistry (IHC).

Clonality: Monoclonal

Anti-CD20 / MS4A1 Antibody Clone: L26

Clone L26 Host and Isotype: Mouse IgG2a kappa

Anti-Human, Baboon, Monkey, Cow (-), Canine (-), Pig (-), and Rat (-) CD20 / MS4A1 Positive Control Sample: Daudi, Raji,, U266,, human lymphocytes. Lymph nodes, tonsils.

Cellular Localization of Antibody Predominantly cell surface with some cytoplasmic

Buffer and Stabilizer: Tissue culture supernatant with 0.05% Azide.

Antibody Concentration: Not applicable

Antibody Purification Method:Culture Supernatant

Immunogen: Human tonsil B cells

Storage Conditions: Store at 2 to 8Â° C (refrigerate). Stable for 24 months when properly stored.

CD20 / MS4A1 Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's CD20 / MS4A1 Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

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