Anti-Oct-2 Specificity Assay (Array)
FFPE human lymph node sections stained with 100 ul anti-Oct-2 (clone OCT2/2137) at 1:50. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.Formalin-fixed, paraffin embedded human tonsil sections stained with 100 ul anti-Oct-2 (clone OCT2/2137) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.Data from SDS-PAGE analysis of Anti-Oct-2 antibody (Clone OCT2/2137). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.Western Blot Analysis Ramos Cell lysate using Oct-2 Mouse Monoclonal Antibody (OCT2/2137).

OCT-2 (POU2F2) (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 158.00$ 348.00
Please Select Product Options Below To View The Catalog Number.

SKU: 5452-MSM2
Species: Human
Tested Applications: ELISA, WB, IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Size
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Shipping Information
In Stock: 1-2 Day Lead Time.
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: 5452-MSM2-P0
OCT-2 (POU2F2) (B-Cell Marker) General Information
Alternate Names
Lymphoid-restricted immunoglobulin octamer-binding protein NF-A2; Oct-2; Octamer-binding protein 2; Octamer-binding transcription factor 2; OTF-2; POU domain class 2 transcription factor 2; POU2F2
Molecular Weight
60kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol5452
Entrez Gene IDPOU2F2
UniProt ID(s)P09086
UniGene ID(s)Hs147381
COSMIC ID Link(s)POU2F2
KEGG Gene ID(s)hsa:5452
General Description of OCT-2 (POU2F2) (B-Cell Marker).
Oct-2 is a transcription factor of the POU homeo-domain family that binds to the Ig gene octamer sites, regulating B-cell-specific genes. Oct-2 expression can be used as a marker of B-cell lineage and differentiation. Germinal center B-cells, mantle B-cells, monocytoid B-cells, and plasma cells show high level expression of Oct-2. Additionally, mantle cell lymphoma, follicular lymphoma, marginal zone lymphoma, plasmacytoma, Burkitt lymphoma, diffuse large cell lymphoma, diffuse large B-cell lymphoma, Hodgkin lymphoma display increased expression of Oct-2. Several studies of Oct-2 expression have shown a low level expression in pre-B, T-cell, myelomonocytic, and epithelial cell lines, whereas all mature B-cell lines have high levels of expression. In spite of scanty evidence for Oct-2 expression in T cells, it is believed that this factor participates in transcriptional regulation during T-cell activation.

Human Anti-OCT-2 (POU2F2) (B-Cell Marker) Antibody Product Attributes

Species: Human
Tested Applications: ELISA, WB, IHC.
Clonality: Monoclonal
Anti-OCT-2 (POU2F2) (B-Cell Marker) Antibody Clone: OCT2/2137
Clone OCT2/2137 Host and Isotype: Mouse IgG1, kappa
Anti-Human OCT-2 (POU2F2) (B-Cell Marker) Positive Control Sample: Raji or U-937 cells. Spleen or Tonsil.
Cellular Localization of Antibody OCT2/2137 Staining: Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human OCT2 protein (apprx. aa 112-297) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

OCT-2 (POU2F2) (B-Cell Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

enQuire Bio's product, OCT-2 (POU2F2) (B-Cell Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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OCT-2 (POU2F2) (B-Cell Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

https://enquirebio.com/wp-content/uploads/2019/01/Anti-Oct-2 Specificity Assay (Array)-300x120.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Oct-2 IHC human Lymph Node (OCT2 2137)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Oct-2 IHC human Tonsil (OCT2 2137)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Anti-Oct-2(OCT2 2137) Gel-193x300.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Oct-2 WB human rhOCT2 and Daudi cells (OCT2 2137)-153x300.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Oct-2 WB human Ramos cells (OCT2 2137)-124x300.jpghttps://enquirebio.com/wp-content/uploads/2018/06/enQuire-Bio-5452-MSM2-P0-anti-OCT-2-POU2F2-B-Cell-Marker-antibody-1-124x300.jpeg