Data from SDS-PAGE analysis of Anti-Ubiquitin antibody (Clone UBB/1748). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.Formalin-fixed, paraffin-embedded human Brain stained with Ubiquitin Mouse Monoclonal Antibody (UBB/1748).

Ubiquitin (Autophagy Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

$ 199.00$ 429.00
Please Select Product Options Below To View The Catalog Number.

SKU: 7314-MSM1
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2c, kappa
Mass Spec Validated?: Not MS Validated

Product NumberDescriptionPrice
7314-MSM1-P0 Size: 20 ug, Tag: Unconjugated $ 199.00
7314-MSM1-P1 Size: 100 ug, Tag: Unconjugated $ 429.00
7314-MSM1-P1ABX Size: 100 ug, Tag: Unconjugated $ 429.00
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In Stock.
Flat Rate Shipping Anywhere in the US: $45
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SKU: 7314-MSM1-P0
Ubiquitin (Autophagy Marker) General Information
Alternate Names
Epididymis secretory protein Li 50; Polyubiquitin B; RPS27A; UBA52; UBA80; UBB; UBC; UBCEP1; UBCEP2; Ubiquitin; Ubiquitin B
Molecular Weight
9kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol7314
Entrez Gene IDUBB
UniProt ID(s)P0CG47; P0CG48; P62979; P62987 and P62988
UniGene ID(s)Hs356190 and 520348
COSMIC ID Link(s)UBB
KEGG Gene ID(s)hsa:7314
General Description of Ubiquitin (Autophagy Marker).
Ubiquitin is a highly conserved and plays an essential role in the ubiquitin-proteasome pathway. In ubiquitination process, it is first activated by forming a thiol-ester complex with the activation component E1, which is then transferred to ubiquitin-carrier protein E2, followed by to ubiquitin ligase E3 for final delivery to epsilon-NH2 of the target protein lysine residue. IkB, p53, cdc25A, Bcl-2 etc. are shown as targets of ubiquitin-proteasome process as part of regulation of cell cycle progression, differentiation, cell stress response, and apoptosis. Moreover, ubiquitin have been reported to bind covalently with pathological inclusions which are resistant to degradation e.g. neurofibrillary tangles/paired helical filaments in Alzheimer's disease, Lewy bodies seen in Parkinson's disease, and Pick bodies found in Pick's disease etc.

Human Anti-Ubiquitin (Autophagy Marker) Antibody Product Attributes

Species: Human
Tested Applications: IHC and western blot.
Clonality: Monoclonal
Anti-Ubiquitin (Autophagy Marker) Antibody Clone: UBB/1748
Clone UBB/1748 Host and Isotype: Mouse IgG2c, kappa
Anti-Human Ubiquitin (Autophagy Marker) Positive Control Sample: HeLa or Jurkat cells. Alzheimer s Brain
Cellular Localization of Antibody UBB/1748 Staining: Cell Surface, Cytoplasmic and Nuclear
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.
Antibody Concentration: 200 ug/ml
Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.
Immunogen: Recombinant fragment of human Ubiquitin protein (apprx. aa 1-119) (Please call for additional information.)
Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Limitations and Warranty

enQuire Bio's product, Ubiquitin (Autophagy Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Tested against >20,000 Human Proteins

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Ubiquitin (Autophagy Marker) Ultraspecific Antibody

Tested against >20,000 Human Proteins

https://enquirebio.com/wp-content/uploads/2019/01/Anti-Ubiquitin Specificity Assay (Array)-300x120.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Ubiquitin IHC human (UBB 1748)-300x225.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Anti-Ubiquitin(UBB 1748) Gel-237x300.jpghttps://enquirebio.com/wp-content/uploads/2019/01/Ubiquitin WB human Raji UBB 1748-110x300.jpghttps://enquirebio.com/wp-content/uploads/2018/06/enQuire-Bio-7314-MSM1-P0-anti-Ubiquitin-Autophagy-Marker-antibody-300x225.jpeg