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Recombinant Human IL 23 Protein

$ 89.00$ 1,200.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10704
Species: Human
Applications: Bioactive
Available Tags: Untagged
Available Hosts: HEK 293
Purity: Greater than 95.0% as determined by analysis by SDS-PAGE.
Length (Amino Acids):

Size
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Shipping Information
1-3 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP10704-2ug
Recombinant Human IL 23 General Information
IL 23  protein 3D structural model from Catalog of Somatic Mutations in Cancer originally published in the paper COSMIC: somatic cancer genetics at high-resolution
Alternate Names
Interleukin 23 alpha subunit p19, Interleukin-12 subunit beta p40, SGRF, IL23P19, IL-23-A, interleukin-six, G-CSF related factor, JKA3 induced upon T-cell activation, interleukin 12B (natural killer cell stimulatory factor 2 cytotoxic lymphocyte maturation factor 2 p40), NK cell stimulatory factor chain 2, Cytotoxic lymphocyte maturation factor 40 kDa subunit, CLMF2, CLMF p40.
Molecular Weight
20.7 kDa
Chromosomal Location
q13.3 on chromosome 12
Curated Database and Bioinformatic Data
Gene SymbolIL23A
Entrez Gene ID51561
UniProt ID(s)Q9NPF7
COSMIC ID Link(s)IL23A
KEGG Gene ID(s)hsa:51561
General Description of Recombinant Human IL 23.
Human IL-23 produced in HEK cells is a 55kDa heterodimeric protein composed of 2 disulfide-linked subunits - 19kDa (p19) and 43 kDa (p40).

Human IL 23 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant IL 23 based upon sequence from Human
Host: QP10704 protein expressed in HEK 293.
Available Tags: Untagged
Protein Construction: A cDNA sequence encoding the sequence of IL 23 was constructred and used to recombinantly synthesize the protein.
Recommended Applications: Bioactive
Application Notes
Recommended Reconstitution Instructions: It is recommended to reconstitute the lyophilized IL23 in sterile 1xPBS containing 0.1% endotoxin-free recombinant HSA.
Bioactivity Data: The activity, as determined by the dose dependent secretion of IL-17 in response to IL-23 using murine splenocytes, the ED50 is 1.9ng/ml.
Monomer or Dimer: Dimer
Amino Acid Sequence: MLGSRAVMLL LLLPWTAQGR AVPGGSSPAW TQCQQLSQKL CTLAWSAHPL VGHMDLREEG DEETTNDVPH IQCGDGCDPQ GLRDNSQFCL QRIHQGLIFY EKLLGSDIFT GEPSLLPDSP VGQLHASLLG LSQLLQPEGH HWETQQIPSL SPSQPWQRLL LRFKILRSLQ AFVAVAARVF AHGAATLSP
Purity: Greater than 95.0% as determined by analysis by SDS-PAGE.
Endotoxin Levels:
Buffer: IL-23 was lyophilized from a 0.1µm filtered solution (1.05 mg/ml) containing 1xPBS.
Storage Conditions: Lyophilized Interleukin-23 although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution IL-23 should be stored at 4°C between 2-7 days and for future use below -18°C. Please prevent freeze-thaw cycles.
Physical Appearance: IL-23 if supplied as a sterile filtered White lyophilized (freeze-dried) powder.

Limitations and Performance Guarantee

enQuire Bio's products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human IL 23 Protein