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Recombinant Human MMP 8 Protein

$ 130.00$ 900.00
Please Select Product Options Below To View The Catalog Number.

SKU: QP10789
Species: Human
Applications: Bioactive
Available Tags: Untagged
Available Hosts: E. Coli
Purity: Greater than 90% as determined by SDS-PAGE.
Length (Amino Acids):

Size
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Shipping Information
1-3 days
Flat Rate Shipping Anywhere in the US: $45
Datasheets and Documentation
Product Datasheet
SKU: QP10789-1U
Recombinant Human MMP 8 General Information
MMP 8  protein 3D structural model from Catalog of Somatic Mutations in Cancer originally published in the paper COSMIC: somatic cancer genetics at high-resolution
Alternate Names
Neutrophil collagenase, EC 3.4. 24.34, Matrix metalloproteinase-8, MMP-8, PMNL collagenase, PMNL-CL, HNC, CLG1.
Molecular Weight
75 kDa
Chromosomal Location
q22.2 on chromosome 11
Curated Database and Bioinformatic Data
Gene SymbolMMP8
Entrez Gene ID4317
UniProt ID(s)P22894
COSMIC ID Link(s)MMP8
KEGG Gene ID(s)hsa:4317
General Description of Recombinant Human MMP 8.
Human Matrix Metalloproteinase-8 produced in E. Coli is a single, non-glycosylated, polypeptide chain having a molecular mass of 75 kDa. The MMP-8 is purified by using an optimized multi-step FPLC method for maximum separation from contaminants.

Human MMP 8 Bioactive Protein Product Attributes

Product Type: Bioactive Protein
Recombinant MMP 8 based upon sequence from Human
Host: QP10789 protein expressed in E. Coli.
Available Tags: Untagged
Protein Construction: A cDNA sequence encoding the sequence of MMP 8 was constructred and used to recombinantly synthesize the protein.
Recommended Applications: Bioactive
Application Notes Used as a standard for analyzing mammalian collagenase activity.
Bioactivity Data: 100 units/ml after activation with APMA by solution assay method. One unit of collagenolytic activity is defined as the cleavage of 1µg of collagen per minute by the solution method.
Amino Acid Sequence: MFSLKTLPFL LLLHVQISKA FPVSSKEKNT KTVQDYLEKF YQLPSNQYQS TRKNGTNVIV EKLKEMQRFF GLNVTGKPNE ETLDMMKKPR CGVPDSGGFM LTPGNPKWER TNLTYRIRNY TPQLSEAEVE RAIKDAFELW SVASPLIFTR ISQGEADINI AFYQRDHGDN SPFDGPNGIL AHAFQPGQGI GGDAHFDAEE TWTNTSANYN LFLVAAHEFG HSLGLAHSSD PGALMYPNYA FRETSNYSLP QDDIDGIQAI YGLSSNPIQP TGPSTPKPCD PSLTFDAITT LRGEILFFKD RYFWRRHPQL QRVEMNFISL FWPSLPTGIQ AAYEDFDRDL IFLFKGNQYW ALSGYDILQG YPKDISNYGF PSSVQAIDAA VFYRSKTYFF VNDQFWRYDN QRQFMEPGYP KSISGAFPGI ESKVDAVFQQ EHFFHVFSGP RYYAFDLIAQ RVTRVARGNK WLNCRYG
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions: |||
Endotoxin Levels:
Buffer: The MMP-8 protein solution (100 units/ml) in 0.05M Tris-HCl buffer, pH 7.6, 0.2M NaCl, 5mM CaCl2, 0.0025% NaN3 and 0.1% BSA.
Storage Conditions: Store at 4°C if entire vial will be used within 2-4 weeks. Store, frozen at -20°C for longer periods of time. Avoid multiple freeze-thaw cycles.
Physical Appearance: Sterile Filtered clear solution.

Limitations and Performance Guarantee

enQuire Bio's products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human MMP 8 Protein