FFPE human prostate carcinoma sections stained with 100 ul anti-PSAP (clone rACPP/1338) at 1:300. HIER epitope retrieval prior to staining was performed in 10mM Citrate, pH 6.0.

Data from SDS-PAGE analysis of Anti-PSAP antibody (Clone rACPP/1338). Reducing lane (R) shows heavy and light chain fragments. NR lane shows intact antibody with expected MW of approximately 150 kDa. The data are consistent with a high purity, intact mAb.

Prostate Specific Acid Phosphatase (PSAP) Ultraspecific Antibody
Tested against >20,000 Human Proteins

Name: Prostate Specific Acid Phosphatase (PSAP) Ultraspecific Antibody <p style="font-size:small">Tested against &gt;20,000 Human Proteins</p>
SKU: 55-MSM4-P0
Availability: InStock

$ 199.00 – $ 429.00

Please Select Product Options Below To View The Catalog Number.

SKU: 55-MSM4
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG1, kappa
Mass Spec Validated?: Not MS Validated

Product Number	Description	Price
55-MSM4-P0	Size: 20 ug, Tag: Unconjugated	$ 199.00
55-MSM4-P1	Size: 100 ug, Tag: Unconjugated	$ 429.00
55-MSM4-P1ABX	Size: 100 ug, Tag: Unconjugated	$ 429.00

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In Stock.

Flat Rate Shipping Anywhere in the US: $45

Datasheets and Documentation

Product Datasheet

Certificate of Analysis and Tags (Coming Soon)

SKU: 55-MSM4-P0

Prostate Specific Acid Phosphatase (PSAP) General Information
Alternate Names
5'-nucleotidase (5'-NT); Acid phosphatase prostate; ACP3; Ecto-5'-nucleotidase; Prostatic acid phosphatase (PAP); Prostatic acid phosphatase; Thiamine monophosphatase (TMPase)
Molecular Weight
52kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol	55
Entrez Gene ID	ACPP
UniProt ID(s)	P15309
UniGene ID(s)	Hs433060
COSMIC ID Link(s)	ACPP
KEGG Gene ID(s)	hsa:55
General Description of Prostate Specific Acid Phosphatase (PSAP).
Recognizes a protein of 52kDa, identified as prostate specific acid phosphatase (PSAP). This enzyme catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.

Human Anti-Prostate Specific Acid Phosphatase (PSAP) Antibody Product Attributes

Species: Human

Tested Applications: IHC.

Clonality: Monoclonal

Anti-Prostate Specific Acid Phosphatase (PSAP) Antibody Clone: rACPP/1338

Clone rACPP/1338 Host and Isotype: Mouse IgG1, kappa

Anti-Human Prostate Specific Acid Phosphatase (PSAP) Positive Control Sample: PC12 cells or normal prostate or prostate carcinoma

Cellular Localization of Antibody rACPP/1338 Staining: Cytoplasmic

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.

Antibody Concentration: 200 ug/ml

Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.

Immunogen: Recombinant full-length human ACPP protein

Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

Prostate Specific Acid Phosphatase (PSAP) Previously Observed Antibody Staining Patterns

Observed Antibody Staining Data By Tissue Type:

Variations in PSAP antibody staining intensity in immunohistochemistry on tissue sections are present across different anatomical locations. An intense signal was observed in glandular cells in the prostate. More moderate antibody staining intensity was present in glandular cells in the prostate. Low, but measureable presence of PSAP could be seen in. We were unable to detect PSAP in other tissues. Disease states, inflammation, and other physiological changes can have a substantial impact on antibody staining patterns. These measurements were all taken in tissues deemed normal or from patients without known disease.

Observed Antibody Staining Data By Tissue Disease Status:

Tissues from cancer patients, for instance, have their own distinct pattern of PSAP expression as measured by anti-PSAP antibody immunohistochemical staining. The average level of expression by tumor is summarized in the table below. The variability row represents patient to patient variability in IHC staining.

Sample Type	breast cancer	carcinoid	cervical cancer	colorectal cancer	endometrial cancer	glioma	head and neck cancer	liver cancer	lung cancer	lymphoma	melanoma	ovarian cancer	pancreatic cancer	prostate cancer	renal cancer	skin cancer	stomach cancer	testicular cancer	thyroid cancer	urothelial cancer
Signal Intensity	-	-	-	-	-	-	-	-	-	-	-	-	-	+++	-	-	-	-	-	-
ACPP Variability	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+	+

Limitations and Warranty

enQuire Bio's product, Prostate Specific Acid Phosphatase (PSAP) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

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Prostate Specific Acid Phosphatase (PSAP) Ultraspecific Antibody Tested against >20,000 Human Proteins