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Recombinant Human PKAR-I alpha Protein

$ 310.00$ 1,530.00
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SKU: QP13062
Species: Human
Applications: See Application Notes
Available Tags: Untagged
Available Hosts: E. Coli
Purity: Greater than 95% as determined by SDS-PAGE.
Length (Amino Acids):

Product NumberDescriptionPrice
QP13062-5ug Size: 5 ug, Tag: Untagged (Native Protein) $ 310.00
QP13062-25ug Size: 25 ug, Tag: Untagged (Native Protein) $ 890.00
QP13062-50ug Size: 50 ug, Tag: Untagged (Native Protein) $ 1,530.00
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In Stock
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Datasheets and Documentation
Product Datasheet
Certificate of Analysis and Tags (Coming Soon)
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Concentration (Write Lyophilized if Lyophilized):

Reconsitution Instructions (Leave Blank if Liquid):

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Bioactivity (test results eg. IU/ml):


SKU: QP13062-5ug
Recombinant Human PKAR-I alpha General Information
Alternate Names
cAMP-dependent protein kinase type I-alpha regulatory subunit, Tissue-specific extinguisher 1, TSE1, PRKAR1A PKR1, PRKAR1, CAR, CNC, CNC1, PKR1, ADOHR, PPNAD1, ACRDYS1.
Molecular Weight
43 kDa
Chromosomal Location
q24.2 on chromosome 17
Curated Database and Bioinformatic Data
Gene SymbolPRKAR1A
Entrez Gene ID5573
UniProt ID(s)P10644
COSMIC ID Link(s)PRKAR1A
KEGG Gene ID(s)hsa:5573
General Description of Recombinant Human PKAR-I alpha.
Human PKA regulatory subunit I a is a dimeric 86kDa protein (the monomer is 381 aa 43kDa). PKAR-I alpha is purified by using an optimized multi-step FPLC method for maximum separation from contaminants.

Human PKAR-I alpha Recombinant Protein Product Attributes

Product Type: Recombinant Protein
Recombinant PKAR-I alpha based upon sequence from Human
Host: QP13062 protein expressed in E. Coli.
Available Tags: Untagged
Protein Construction: A cDNA sequence encoding the sequence of PKAR-I alpha was constructred and used to recombinantly synthesize the protein.
Recommended Applications: See Application Notes
Application Notes
Other Applications: The cAMP-dependent protein kinase, regulatory subunit RIa reversibly inhibits the catalytic subunit Ca of the cAMP-dependent protein kinase PKA. The inhibition of the catalytic subunit can be reversed by the addition of the second messenger cAMP.
Bioactivity Data: Untested
Monomer or Dimer: Dimer
Amino Acid Sequence: MESGSTAASE EARSLRECEL YVQKHNIQAL LKDSIVQLCT ARPERPMAFL REYFERLEKE EAKQIQNLQK AGTRTDSRED EISPPPPNPV VKGRRRRGAI SAEVYTEEDA ASYVRKVIPK DYKTMAALAK AIEKNVLFSH LDDNERSDIF DAMFSVSFIA GETVIQQGDE GDNFYVIDQG ETDVYVNNEW ATSVGEGGSF GELALIYGTP RAATVKAKTN VKLWGIDRDS YRRILMGSTL RKRKMYEEFL SKVSILESLD KWERLTVADA LEPVQFEDGQ KIVVQGEPGD EFFIILEGSA AVLQRRSENE EFVEVGRLGP SDYFGEIALL MNRPRAATVV ARGPLKCVKL DRPRFERVLG PCSDILKRNI QQYNSFVSLS V
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: |||
Endotoxin Levels: Not Determined. Testing recommended prior to use in cell culture and can be performed upon request.
Buffer: PKA regulatory subunit-I alpha is supplied at a concentration of 1.3 mg/ml in 20mM MOPS (pH 7.0), 150mM NaCl, 1mM 2-mercaptoethanol and 50% glycerol.
Storage Conditions: PKAR-Ia should be stored at 4°C if entire vial will be used within 2-4 weeks. For long term storage it is recommended to store at -20°C. Avoid multiple freeze-thaw cycles.
Physical Appearance: Sterile Filtered clear solution.

Limitations and Performance Guarantee

enQuire Bio's products are guaranteed and approved for RESEARCH USE ONLY or manufacturing purposes. This product may not be used as a pharmaceutical agent, or other product intended for human consumption without meeting additional regulatory requirements. This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.

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Recombinant Human PKAR-I alpha Protein