PDF DatasheetHuman Histone chaperone ASF1A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Histone chaperone ASF1A based upon sequence from: Human
Host: QP8277 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Histone chaperone ASF1A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8277.
Bioactivity Data: Untested
Full Length? Full Length
Amino Acid Sequence: MAKVQVNNVV VLDNPSPFYN PFQFEITFEC IEDLSEDLEW KIIYVGSAES EEYDQVLDSV LVGPVPAGRH MFVFQADAPN PGLIPDADAV GVTVVLITCT YRGQEFIRVG YYVNNEYTET ELRENPPVKP DFSKLQRNIL ASNPRVTRFH INWEDNTEKL EDAESSNPNL QSLLSTDALP SASKGWSTSE NSLNVMLESH MDCM
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Histone chaperone ASF1A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Histone chaperone ASF1A Protein General Information | |
|---|---|
| Alternate Names | |
| CGI-98; HSPC146; CIA | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | ASF1A |
| Entrez Gene ID | 25842 |
| Ensemble Gene ID | ENSG00000111875 |
| RefSeq Protein Accession(s) | NP_054753.1 |
| RefSeq mRNA Accession(s) | NM_014034.2 |
| UniProt ID(s) | Q9Y294 |
| UniGene ID(s) | Hs.292316 |
| HGNC ID(s) | HGNC:20995 |
| COSMIC ID Link(s) | ASF1A |
| KEGG Gene ID(s) | hsa:25842 |
| PharmGKB ID(s) | PA128394636 |
| General Description of Recombinant Human Histone chaperone ASF1A Protein. | |
| Histone chaperone that facilitates histone deposition and histone exchange and removal during nucleosome assembly and disassembly. Cooperates with chromatin assembly factor 1 (CAF-1) to promote replication-dependent chromatin assembly and with HIRA to promote replication-independent chromatin assembly. Required for the formation of senescence-associated heterochromatin foci (SAHF) and efficient senescence-associated cell cycle exit. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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