PDF DatasheetHuman Protein unc-119 homolog A Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Protein unc-119 homolog A based upon sequence from: Human
Host: QP7593 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Protein unc-119 homolog A, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7593.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Pro240
Amino Acid Sequence: MKVKKGGGGA GTATESAPGP SGQSVAPIPQ PPAESESGSE SEPDAGPGPR PGPLQRKQPI GPEDVLGLQR ITGDYLCSPE ENIYKIDFVR FKIRDMDSGT VLFEIKKPPV SERLPINRRD LDPNAGRFVR YQFTPAFLRL RQVGATVEFT VGDKPVNNFR MIERHYFRNQ LLKSFDFHFG FCIPSSKNTC EHIYDFPPLS EELISEMIRH PYETQSDSFY FVDDRLVMHN KADYSYSGTP
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Protein unc-119 homolog A Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Protein unc-119 homolog A Protein General Information | |
|---|---|
| Alternate Names | |
| HRG4; IMD13; POC7A; POC7 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | UNC119 |
| Entrez Gene ID | 9094 |
| Ensemble Gene ID | ENSG00000109103 |
| RefSeq Protein Accession(s) | NP_001317095.1 |
| RefSeq mRNA Accession(s) | NM_001330166.1, NM_005148.3, NM_054035.2 |
| UniProt ID(s) | Q13432 |
| UniGene ID(s) | Hs.410455 |
| HGNC ID(s) | HGNC:12565 |
| COSMIC ID Link(s) | UNC119 |
| KEGG Gene ID(s) | hsa:9094 |
| PharmGKB ID(s) | PA37202 |
| General Description of Recombinant Human Protein unc-119 homolog A Protein. | |
| Involved in synaptic functions in photoreceptor cells, the signal transduction in immune cells as a Src family kinase activator, endosome recycling, the uptake of bacteria and endocytosis, protein trafficking in sensory neurons and as lipid-binding chaperone with specificity for a diverse subset of myristoylated proteins. Specifically binds the myristoyl moiety of a subset of N-terminally myristoylated proteins and is required for their localization. Binds myristoylated GNAT1 and is required for G-protein localization and trafficking in sensory neurons. Probably plays a role in trafficking proteins in photoreceptor cells. Plays important roles in mediating Src family kinase signals for the completion of cytokinesis via RAB11A. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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