PDF DatasheetHuman MORC family CW-type zinc finger protein 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant MORC family CW-type zinc finger protein 3 based upon sequence from: Human
Host: QP7595 protein expressed in E. coli.
Tag: His-SUMO
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) MORC family CW-type zinc finger protein 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP7595.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: Met1 – Tyr290
Amino Acid Sequence: MAAQPPRGIR LSALCPKFLH TNSTSHTWPF SAVAELIDNA YDPDVNAKQI WIDKTVINDH ICLTFTDNGN GMTSDKLHKM LSFGFSDKVT MNGHVPVGLY GNGFKSGSMR LGKDAIVFTK NGESMSVGLL SQTYLEVIKA EHVVVPIVAF NKHRQMINLA ESKASLAAIL EHSLFSTEQK LLAELDAIIG KKGTRIIIWN LRSYKNATEF DFEKDKYDIR IPEDLDEITG KKGYKKQERM DQIAPESDYS LRAYCSILYL KPRMQIILRG QKVKTQLVSK SLAYIERDVY
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human MORC family CW-type zinc finger protein 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human MORC family CW-type zinc finger protein 3 Protein General Information | |
|---|---|
| Alternate Names | |
| NXP2; ZCW5; ZCWCC3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | MORC3 |
| Entrez Gene ID | 23515 |
| Ensemble Gene ID | ENSG00000159256 |
| RefSeq Protein Accession(s) | NP_056173.1 |
| RefSeq mRNA Accession(s) | NM_015358.2 |
| UniProt ID(s) | Q14149 |
| UniGene ID(s) | Hs.421150 |
| HGNC ID(s) | HGNC:23572 |
| COSMIC ID Link(s) | MORC3 |
| KEGG Gene ID(s) | hsa:23515 |
| PharmGKB ID(s) | PA128394632 |
| General Description of Recombinant Human MORC family CW-type zinc finger protein 3 Protein. | |
| Nuclear factor which forms MORC3-NBs (nuclear bodies) via an ATP-dependent mechanism (PubMed:20501696). Sumoylated MORC3-NBs can also associate with PML-NBs (PubMed:20501696). Recruits TP53 and SP100 to PML-NBs, thus regulating TP53 activity (PubMed:17332504). Binds RNA in vitro (PubMed:11927593). May be required for influenza A transcription during viral infection (PubMed:26202233). | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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