PDF DatasheetHuman Ras-related C3 botulinum toxin substrate 3 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Ras-related C3 botulinum toxin substrate 3 based upon sequence from Human
Host: QP6576 protein expressed in E. coli.
Tag: GST
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Ras-related C3 botulinum toxin substrate 3, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Recommended Applications: Immunogen, Protein Standard, Cell culture, or Other Cell Biology Applications.
Application Notes: Please contact us for application specific information for QP6576.
Bioactivity Data: Untested
Full Length? Full Length
Expression Region: Met1 – Cys192
Amino Acid Sequence: MQAIKCVVVG DGAVGKTCLL ISYTTNAFPG EYIPTVFDNY SANVMVDGKP VNLGLWDTAG QEDYDRLRPL SYPQTDVFLI CFSLVSPASF ENVRAKWYPE VRHHCPHTPI LLVGTKLDLR DDKDTIERLR DKKLAPITYP QGLAMAREIG SVKYLECSAL TQRGLKTVFD EAIRAVLCPP PVKKPGKKC
Purity: Greater than 80% as determined by SDS-PAGE.
Reconstitution Instructions: Concentrated protein in liquid format. Reconstitution is not necessary.
Concentration of Human Ras-related C3 botulinum toxin substrate 3 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Ras-related C3 botulinum toxin substrate 3 Protein General Information | |
|---|---|
| Curated Database and Bioinformatic Data | |
| Gene Symbol | RAC3 |
| Entrez Gene ID | 5881 |
| Ensemble Gene ID | ENSG00000169750 |
| RefSeq Protein Accession(s) | NP_005043.1 |
| RefSeq mRNA Accession(s) | NM_005052.2 |
| UniProt ID(s) | P60763 |
| UniGene ID(s) | Hs.45002 |
| HGNC ID(s) | HGNC:9803 |
| COSMIC ID Link(s) | RAC3 |
| KEGG Gene ID(s) | hsa:5881 |
| PharmGKB ID(s) | PA34164 |
| General Description of Recombinant Human Ras-related C3 botulinum toxin substrate 3 Protein. | |
| Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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