PDF DatasheetHuman Transcription termination factor 1 Recombinant Protein Product Attributes
Product Type: Recombinant Protein
Recombinant Transcription termination factor 1 based upon sequence from: Human
Host: QP8725 protein expressed in E. coli.
Tag: His
Protein Construction: A DNA sequence encoding the Homo sapiens (Human) Transcription termination factor 1, was expressed in the hosts and tags indicated. Please select your host/tag option, above.
Application Notes: Please contact us for application specific information for QP8725.
Bioactivity Data: Untested
Full Length? Partial (see sequence information for more details).
Expression Region: His11 – Ala242
Amino Acid Sequence: HTPVSDKKKK KCSIHKERPQ KHSHEIFRDS SLVNEQSQIT RRKKRKKDFQ HLISSPLKKS RICDETANAT STLKKRKKRR YSALEVDEEA GVTVVLVDKE NINNTPKHFR KDVDVVCVDM SIEQKLPRKP KTDKFQVLAK SHAHKSEALH SKVREKKNKK HQRKAASWES QRARDTLPQS ESHQEESWLS VGPGGEITEL PASAHKNKSK KKKKKSSNRE YETLAMPEGS QA
Purity: Greater than 90% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human Transcription termination factor 1 Protein:
Endotoxin Levels: Not determined.
Buffer: Tris-based buffer, 50% glycerol
Storage Conditions: Store at -20C to -80C.
| Recombinant Human Transcription termination factor 1 Protein General Information | |
|---|---|
| Alternate Names | |
| TTF-1; TTF-I | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | TTF1 |
| Entrez Gene ID | 7270 |
| Ensemble Gene ID | ENSG00000125482 |
| RefSeq Protein Accession(s) | NP_001192225.1 |
| RefSeq mRNA Accession(s) | NM_001205296.1, NM_007344.3, XM_006717273.3 |
| UniProt ID(s) | Q15361 |
| UniGene ID(s) | Hs.54780 |
| HGNC ID(s) | HGNC:12397 |
| COSMIC ID Link(s) | TTF1 |
| KEGG Gene ID(s) | hsa:7270 |
| PharmGKB ID(s) | PA37062 |
| General Description of Recombinant Human Transcription termination factor 1 Protein. | |
| Multifunctional nucleolar protein that terminates ribosomal gene transcription, mediates replication fork arrest and regulates RNA polymerase I transcription on chromatin. Plays a dual role in rDNA regulation, being involved in both activation and silencing of rDNA transcription. Interaction with BAZ2A/TIP5 recovers DNA-binding activity. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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