PDF DatasheetHuman Anti-HCG-beta Antibody Product Attributes
Species: Human
Tested Applications: Immunohistochemistry (IHC).
Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml for 30 minutes at RT)
Clonality: Monoclonal
Anti-HCG-beta Antibody Clone: HCGb/54 + HCGb/459
Clone HCGb/54 + HCGb/459 Host and Isotype: Mouse IgG
Anti-Human HCG-beta Positive Control Sample: Placenta
Cellular Localization of Antibody Cytoplasmic, Secreted
Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.
Antibody Concentration: 200ug/ml
Antibody Purification Method:Protein A/G Purified
Immunogen: Recombinant hCG beta protein (HCGb/54, HCGb/459)
Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.
HCG-beta Previously Observed Antibody Staining Patterns
| HCG-beta General Information | |
|---|---|
| Alternate Names | |
| Retinol binding protein 4, plasma RBP4 | |
| Molecular Weight | |
| 22kDa | |
| Chromosomal Location | |
| 19q13.33 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CGB |
| Entrez Gene ID | 1082 |
| Ensemble Gene ID | ENSG00000104827 |
| RefSeq Protein Accession(s) | NP_000728 |
| RefSeq mRNA Accession(s) | NM_000737 |
| RefSeq Genomic Accession(s) | NC_000019, NC_018930 |
| UniProt ID(s) | P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0 |
| UniGene ID(s) | P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0 |
| HGNC ID(s) | 1886 |
| Cosmic ID(s) | CGB3 |
| KEGG Gene ID(s) | hsa:1082 |
| General Description of HCG-beta. | |
| This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha, beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). hCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior. | |
Limitations and Warranty
enQuire Bio’s HCG-beta Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.
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