Anti-HCG-beta Antibody Clone SPM529

$ 488.00

SKU: 1082-MSM2X
Species: Human
Tested Applications: Immunohistochemistry (IHC)
Available Conjugates: Unconjugated
Isotype: Mouse IgG1
Mass Spec Validated?: Not MS Validated

PDF Datasheet

Human Anti-HCG-beta Antibody Product Attributes

Species: Human

Tested Applications: Immunohistochemistry (IHC).

Application Notes: Immunohistochemistry (IHC) (Formalin-fixed) (0.5-1ug of antibody/ml, 30 min RT)

Clonality: Monoclonal

Anti-HCG-beta Antibody Clone: SPM529

Clone SPM529 Host and Isotype: Mouse IgG1

Anti-Human HCG-beta Positive Control Sample: Placenta

Cellular Localization of Antibody Cytoplasmic, Secreted

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide.

Antibody Concentration: 200ug/ml

Antibody Purification Method:Protein A/G Purified

Immunogen: Recombinant hCG beta protein

Storage Conditions: Store at 2 to 8° C (refrigerate). Stable for 24 months when properly stored.

HCG-beta Previously Observed Antibody Staining Patterns

HCG-beta General Information

Alternate Names

Retinol binding protein 4, plasma RBP4

Molecular Weight

22kDa

Chromosomal Location

19q13.33

Curated Database and Bioinformatic Data

Gene Symbol CGB

Entrez Gene ID 1082

Ensemble Gene ID ENSG00000104827

RefSeq Protein Accession(s) NP_000728

RefSeq mRNA Accession(s) NM_000737

RefSeq Genomic Accession(s) NC_000019, NC_018930

UniProt ID(s) P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0

UniGene ID(s) P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0

HGNC ID(s) 1886

Cosmic ID(s) CGB3

KEGG Gene ID(s) hsa:1082

General Description of HCG-beta.

This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha, beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). hCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Limitations and Warranty

enQuire Bio’s HCG-beta Anti-Human Monoclonal is available for Research Use Only. This antibody is guaranteed to work for a period of two years when properly stored.

Size

100 ug

Tag

Unconjugated

Buffer and Stabilizer

10mM PBS with 0.05% BSA & 0.05% azide.

Product Type

Host

Isotype

Applications

Species

Mass Spec Validated?

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HCG-beta General Information
Alternate Names
Retinol binding protein 4, plasma RBP4
Molecular Weight
22kDa
Chromosomal Location
19q13.33
Curated Database and Bioinformatic Data
Gene Symbol	CGB
Entrez Gene ID	1082
Ensemble Gene ID	ENSG00000104827
RefSeq Protein Accession(s)	NP_000728
RefSeq mRNA Accession(s)	NM_000737
RefSeq Genomic Accession(s)	NC_000019, NC_018930
UniProt ID(s)	P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
UniGene ID(s)	P01233, A0A0F7RQP8, Q3SY41, Q8WXL4, Q3KPI3, Q8WXL1, P0DN86, Q8WXL3, B9ZVP5, Q14000, Q8WXL2, Q13991, Q8WTT5, A1A5E0
HGNC ID(s)	1886
Cosmic ID(s)	CGB3
KEGG Gene ID(s)	hsa:1082
General Description of HCG-beta.
This MAb reacts with a protein of 22kDa, identified as beta sub-unit of HCG. It does not cross react with the alpha sub-unit. HCG is a glycoprotein, which is secreted in large quantities by normal trophoblasts. It is present only in trace amounts in non-pregnant urine, sera but rises sharply during pregnancy. HCG is composed of two non-identical, non-covalently linked polypeptide chains designated as the alpha, beta subunits. The beta subunit is identical to that of thyroid stimulating hormone (TSH), follicle stimulating hormone (FSH),, luteinizing hormone (LH). hCG MAb detects cells, tumors of trophoblastic origin such as choriocarcinoma. Large cell carcinoma, adenocarcinoma of the lung demonstrate anti-hCG positivity in 90%, 60% of cases respectively. 20% of lung squamous cell carcinomas are positive. hCG expression by non-trophoblastic tumors may indicate aggressive behavior.

Anti-HCG-beta Antibody Clone SPM529

Human Anti-HCG-beta Antibody Product Attributes

HCG-beta Previously Observed Antibody Staining Patterns

Limitations and Warranty

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