Formalin-fixed, paraffin-embedded human Tonsil stained with CD103 Mouse Monoclonal Antibody (ITGAE/2474).

SDS-PAGE Analysis Purified CD103 Mouse Monoclonal Antibody (ITGAE/2474).Confirmation of Purity and Integrity of Antibody.

Analysis of Protein Array containing more than 19,000 full-length human proteins using CD103 Mouse Monoclonal Antibody (ITGAE/2474). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (MAb) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProtTM array. Z-scores are described in units of standard deviations (SDs) above the mean value of all signals generated on that array. If targets on HuProtTM are arranged in descending order of the Z-score, the S-score is the difference (also in units of SDs) between the Z-score. S-score therefore represents the relative target specificity of a MAb to its intended target. A MAb is considered to specific to its intended target, if the MAb has an S-score of at least 2.5. For example, if a MAb binds to protein X with a Z-score of 43 and to protein Y with a Z-score of 14, then the S-score for the binding of that MAb to protein X is equal to 29.

Formalin-fixed, paraffin-embedded human Colon stained with CD103 Mouse Monoclonal Antibody (ITGAE/2474).

CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Ultraspecific Antibody
Tested against >20,000 Human Proteins

Name: CD103 / Integrin alpha E (T-Cell Lymphoma &amp; Hairy Cell Leukemia Marker) Ultraspecific Antibody <p style="font-size:small">Tested against &gt;20,000 Human Proteins</p>
SKU: 3682-MSM4-P0
Availability: InStock

$ 228.00 – $ 488.00

SKU: 3682-MSM4
Species: Human
Tested Applications: IHC
Available Conjugates: Unconjugated
Isotype: Mouse IgG2b, kappa
Mass Spec Validated?: Not MS Validated

Size

Buffer and Stabilizer

Clear

SKU: 3682-MSM4-P0 Categories: Antibody, Human, IgG2b, IHC, kappa, Mouse, Not MS Validated, Ultraspecific Antibodies, Unconjugated Tag: CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker)

PDF Datasheet

Human Anti-CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody Product Attributes

Species: Human

Tested Applications: IHC.

Clonality: Monoclonal

Anti-CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody Clone: ITGAE/2474

Clone ITGAE/2474 Host and Isotype: Mouse IgG2b, kappa

Anti-Human CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Positive Control Sample: Tonsil, Colon or Stomach

Cellular Localization of Antibody ITGAE/2474 Staining: Cell Surface and Cytoplasmic

Buffer and Stabilizer: 10mM PBS with 0.05% BSA & 0.05% azide. Also available without BSA & Azide.

Antibody Concentration: 200 ug/ml

Antibody Purification Method:Protein A/G purified from Bioreactor concentrate.

Immunogen: Recombinant human ITGAE protein fragment (Please call for additional information.)

Storage Conditions: Store at 2 to 8 C (refrigerate). Stable for 24 months when properly stored.

CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Previously Observed Antibody Staining Patterns

CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) General Information
Alternate Names
CD103; Human mucosal lymphocyte antigen 1 (HML1 antigen); Integrin alpha E heavy chain; Integrin alpha E light chain; Integrin alpha E, epithelial-associated; Integrin alpha E1; Integrin alpha-IEL (intestinal intraepithelial lymphocytes); Integrin alpha M290; Integrin alpha-E heavy chain; Integrin, alpha E (ITGAE)
Molecular Weight
150kDa
Chromosomal Location
Ships on blue ice.
Curated Database and Bioinformatic Data
Gene Symbol	3682
Entrez Gene ID	ITGAE
UniProt ID(s)	P38570
UniGene ID(s)	Hs513867
COSMIC ID Link(s)	ITGAE
KEGG Gene ID(s)	hsa:3682
General Description of CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker).
This MAb recognizes a protein of 150kDa, identified as CD103, which is the alpha-E integrin subunit of the heterodimeric alpha-E beta-7 (aEb7) integrin belonging to a small beta-7 integrin subfamily. CD103 is expressed on more than 95% of intraepithelial CD8+ cells and on 40% of mucosa-associated T cells, whereas less than 2% of resting blood lymphocytes are CD103-positive. In several malignant conditions, such as T-cell lymphomas and hairy cell leukemia (HCL), the cells express CD103. Antibody to CD103 is an extremely useful addition to the IHC panel for the diagnosis of hairy cell leukemia (HCL).

Limitations and Warranty

enQuire Bio’s product, CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) MonoSpecific Antibody, is available for Research Use Only (RUO-Only). This antibody is guaranteed to work for a period of two years when properly stored.

Size	20 ug, 100 ug
Tag	Unconjugated
Buffer and Stabilizer	10mM PBS with 0.05% BSA and 0.05% Azide, PBS (BSA and Azide Free)
Product Type	Antibody
Host	Mouse
Species	Human
Isotype	IgG2b, kappa
Mass Spec Validated?	Not MS Validated
Applications	IHC

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CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Ultraspecific Antibody Tested against >20,000 Human Proteins

Human Anti-CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Antibody Product Attributes

CD103 / Integrin alpha E (T-Cell Lymphoma & Hairy Cell Leukemia Marker) Previously Observed Antibody Staining Patterns

Limitations and Warranty

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