PDF DatasheetHuman BDNF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant BDNF based upon sequence from: Human
Host: QP5220 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5220.
Bioactivity Data: To pass QC, Human BDNF must induce C6 cell proliferation significantly at concentrations less than 2 ug/ml, or activity of at least 5.0 x 10^2 units/mg (typical ED50 is less than 1 ug/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: MHSDPARRGE LSVCDSISEW VTAADKKTAV DMSGGTVTVL EKVPVSKGQL KQYFYETKCN PMGYTKEGCR GIDKRHWNSQ CRTTQSYVRA LTMDSKKRIG WRFIRIDTSC VCTLTIKRGR
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human BDNF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human BDNF Protein General Information | |
|---|---|
| Alternate Names | |
| BDNF, BDNF protein, Brain-derived neurotrophic factor | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | BDNF |
| Entrez Gene ID | 627 |
| Ensemble Gene ID | ENSG00000176697 |
| RefSeq Protein Accession(s) | NP_001137277.1 |
| RefSeq mRNA Accession(s) | NM_001143805.1, NM_001143806.1, NM_001143807.1, NM_001143808.1, NM_001143809.1, NM_001143810.1, NM_001143811.1, NM_001143812.1, NM_001143813.1, NM_001143814.1, NM_001143816.1, NM_001709.4, NM_170731.4, NM_170732.4, NM_170733.3, NM_170734.3, NM_170735.5, XM_011520280.2 |
| UniProt ID(s) | P23560 |
| UniGene ID(s) | Hs.502182 |
| HGNC ID(s) | HGNC:1033 |
| COSMIC ID Link(s) | BDNF |
| KEGG Gene ID(s) | hsa:627 |
| PharmGKB ID(s) | PA31891 |
| General Description of Recombinant Human BDNF Protein . | |
| Brain-derived neurotrophic factor (BDNF) is a nerve growth factor that binds two receptors, the low-affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase B (TrkB), to support neuron growth and survival. BDNF expression in the hippocampus is essential for long-term memory storage and learning. Human, mouse, rat, and pig BDNF are cross-reactive. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
There are no reviews yet.