PDF DatasheetHuman CCL13 / MCP-4 Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CCL13 / MCP-4 based upon sequence from: Human
Host: QP5255 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5255.
Bioactivity Data: Human CCL13 / MCP-4 induces THP-1 chemotaxis (significanty different from control at Human CCL13 / MCP-4 concentrations greater than 1 ug/ml).
Monomer or Dimer: Monomer
Amino Acid Sequence: QPDALNVPST CCFTFSSKKI SLQRLKSYVI TTSRCPQKAV IFRTKLGKEI CADPKEKWVQ NYMKHLGRKA HTLKT
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CCL13 / MCP-4 Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CCL13 / MCP-4 Protein General Information | |
|---|---|
| Alternate Names | |
| CCL13, MCP-4, NCC1, SCYL1, NCC-1, SCYA13, CKb10, MCP-4 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CCL13 |
| Entrez Gene ID | 6357 |
| Ensemble Gene ID | ENSG00000181374 |
| RefSeq Protein Accession(s) | NP_005399.1 |
| RefSeq mRNA Accession(s) | NM_005408.2 |
| UniProt ID(s) | Q99616 |
| UniGene ID(s) | Hs.414629 |
| HGNC ID(s) | HGNC:10611 |
| COSMIC ID Link(s) | CCL13 |
| KEGG Gene ID(s) | hsa:6357 |
| PharmGKB ID(s) | PA35544 |
| General Description of Recombinant Human CCL13 / MCP-4 Protein . | |
| Monocyte chemotactic protein 4 (MCP-4), also called CCL13, is induced by inflammatory proteins such as interleukin 1 (IL-1) and tumor necrosis factor alpha (TNFa). MCP-4 is a ligand for the G protein coupled chemokine receptors CCR2, CCR3, and CCR5. MCP-4 activates signaling in monocytes, T lymphocytes, eosinophils, and basophils during inflammation and allergic responses. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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