PDF DatasheetHuman CTGF Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CTGF based upon sequence from: Human
Host: QP5373 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP5373.
Bioactivity Data: Bioactivity of Human CTGF confirmed in HUVEC cell proliferation assay.
Monomer or Dimer: Monomer
Amino Acid Sequence: MGKKCIRTP K ISKPIKFE LS GCTSMKT YRA KFCGVC TDGR CCTPH RTTTL PVEF KCPDGE VMK KNMMFIK TC ACHYNCPG D NDIFESLYY RKMYGDMA
Purity: Greater than 90 as determined by SDS-PAGE.
Reconstitution Instructions:
Concentration of Human CTGF Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CTGF Protein General Information | |
|---|---|
| Alternate Names | |
| CCN2, NOV2, HCS24, IGFBP8 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CTGF |
| Entrez Gene ID | 1490 |
| Ensemble Gene ID | ENSG00000118523 |
| RefSeq Protein Accession(s) | NP_001892.1 |
| RefSeq mRNA Accession(s) | NM_001901.2 |
| UniProt ID(s) | P29279 |
| UniGene ID(s) | Hs.410037 |
| HGNC ID(s) | HGNC:2500 |
| COSMIC ID Link(s) | CTGF |
| KEGG Gene ID(s) | hsa:1490 |
| PharmGKB ID(s) | PA27003 |
| General Description of Recombinant Human CTGF Protein . | |
| Connective tissue growth factor (CTGF) is a mitogen that is secreted by vascular endothelial cells in response to basic fibroblast growth factor (bFGF) or vascular endothelial growth factor (VEGF). CTGF promotes cell growth, migration, adhesion, and survival of endothelial cells. CTGF is also important during osteogenesis, chondrogenesis, and skeletogenesis. CTGF has an insulin-like growth factor binding protein (IGFBP) domain, a thrombospondin type 1 repeat (TSR) domain, and a C-terminal cysteine knot motif. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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