PDF DatasheetHuman CXCL1 / GRO-alpha Bioactive Protein Product Attributes
Product Type: Bioactive Protein
Recombinant CXCL1 / GRO-alpha based upon sequence from Human
Host: QP1008 protein expressed in E. coli.
Tag: Untagged
Recommended Applications: Bioactive
Application Notes: Please contact us for application specific information for QP1008.
Bioactivity Data: Bioactivity confirmed by human neutrophil chemotaxis assay (significanty different from control at Human CXCL1 / GRO-alpha concentrations greater than 10 ng/ml)
Monomer or Dimer: Monomer
Amino Acid Sequence: ASVATELRCQ CLQTLQGIHP KNIQSVNVKS PGPHCAQTEV IATLKNGRKA CLNPASPIVK KIIEKMLNSD KSN
Purity: Greater than 95% as determined by SDS-PAGE.
Reconstitution Instructions: A Certificate of Analysis (CofA) will be sent along with the protein and will contain the proper reconstitution instructions.
Concentration of Human CXCL1 / GRO-alpha Protein: Lyophilized. Concentration determined by reconstitution volume.
Endotoxin Levels: Less than or equal to 1.00 EUs/ug as determined by the LAL method.
Buffer: Sterile filtered (0.22 um) solution containing 0.1% TFA
Storage Conditions: Store at -20C to -80C lyophilized. Guaranteed for 1 year at -80C reconstituted and 3 months at 4C reconstituted.
| Recombinant Human CXCL1 / GRO-alpha Protein General Information | |
|---|---|
| Alternate Names | |
| CXCL1, MGSA, NAP-3, SCYB1, GROa, MGSA-a, GRO1, FSP, MGSA, NAP-3 | |
| Curated Database and Bioinformatic Data | |
| Gene Symbol | CXCL1 |
| Entrez Gene ID | 2919 |
| Ensemble Gene ID | ENSG00000163739 |
| RefSeq Protein Accession(s) | NP_001502.1 |
| RefSeq mRNA Accession(s) | NM_001511.3 |
| UniProt ID(s) | P09341 |
| UniGene ID(s) | Hs.708652 |
| HGNC ID(s) | HGNC:4602 |
| COSMIC ID Link(s) | CXCL1 |
| KEGG Gene ID(s) | hsa:2919 |
| PharmGKB ID(s) | PA35050 |
| General Description of Recombinant Human CXCL1 / GRO-alpha Protein . | |
| Growth regulated protein alpha (GRO-alpha), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GRO-alpha is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GRO-alpha signals through the CXCR2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing. | |
Limitations and Performance Guarantee
This is a life science research product (for Research Use Only). This product is guaranteed to work for a period of two years when stored at -70C or colder, and one year when aliquoted and stored at -20C.
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